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HENAN SUNLAKE ENTERPRISE CORPORATIONCabozantinib Malate//file1.lookchem.com/300w/substances/2022-02-14-06/c0bc4631-bfbc-4e29-b310-a025eb81f7c2.png
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Cabozantinib Malate CAS NO.1140909-48-3

Min.Order Quantity:
1 Kilogram
Purity:
98%
Port:
China Main Port
Payment Terms:
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Product Details

Keywords

  • Cabozantinib Malate
  • 1140909-48-3
  • C32H30FN3O10

Quick Details

  • ProName: Cabozantinib Malate
  • CasNo: 1140909-48-3
  • Molecular Formula: C32H30FN3O10
  • Appearance: powder
  • Application: 1140909-48-3
  • DeliveryTime: within 3-7 days
  • PackAge: as requested
  • Port: China Main Port
  • ProductionCapacity: 300 Kilogram/Month
  • Purity: 98%
  • Storage: store in cool, dry place
  • Transportation: by sea or by air
  • LimitNum: 1 Kilogram

Superiority

cabozantinib malate basic information
product name: cabozantinib malate
synonyms: (2s)-2-hydroxybutanedioic acid compd. with n-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1);cabozantinib (s)-malate;cabozantinib l-malate salt;n-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (2s)-;cabozantinib (s)-malate(xl-184);cabozantinib l-malate;cabozantinib malate (xl184);xl-184 (malate)
cas: 1140909-48-3
mf: c32h30fn3o10
mw: 635.5931032
einecs:
product categories: inhibitors
mol file: 1140909-48-3.mol
cabozantinib malate structure
cabozantinib malate chemical properties
safety information
msds information
cabozantinib malate usage and synthesis
chemical properties off-white solid
usage cabozantinib is a small molecule c-met modulator. cabozantinib acts as a potent multitargeted vegfr2, met, flt3, tie2, kit and ret inhibitor with ic50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nm for vegfr2, met, flt3, tie2 and kit, respectively. cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell a poptosis.
usage xl184 (cabozantinib, bms-907351) is a potent multitargeted vegfr2, met, flt3, tie2, kit and ret inhibitor with ic50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nm for vegfr2, met, flt3, tie2 and kit, respectively.
usage cabozantinib malate is the malate of cabozantinib, a potent vegfr2 inhibitor with ic50 of 0.035 nm and also inhibits c-met, ret, kit, flt-1/3/4, tie2, and axl with ic50 of 1.3 nm, 4 nm, 4.6 nm, 12 nm/11.3 nm/6 nm, 14.3 nm and 7 nm, respectively.
cabozantinib malate preparation products and raw materials

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