Citrus Aurantium?Extract Hesperidin Nobiletin Citrus fruit extract CAS NO.520-26-3

specification:

[brief introduction of hesperidin]

hesperidin is also referred to by names like bioflavonoid, citrus bioflavonoid, and hesperin methyl-chalcone. hesperidin alone, or in combination with other citrus bioflavonoids (diosmin, for example), is most often used for blood vessel conditions such as hemorrhoids, varicose veins, and poor circulation (venous stasis). it is also used to treat lymphedema, a condition involving fluid retention that can be a complication of breastcancer surgery.internal hemorrhoids, when used in combination with diosmin.

possibly ineffective for:

reducing arm swelling in lymphedema following surgery for breastcancer.

insufficient evidence for:

varicose veins.

other conditions.

more evidence is needed to rate the effectiveness of hesperidin for these uses.

hesperidin side effects & safety

hesperidin is possibly safe for most people when used for less than six months. the safety of using it for a longer period of time is unknown. side effects include stomach pain and upset, diarrhea, and headache.

special precautions & warnings:

pregnancy and breast-feeding: not enough is known about the use of hesperidin during pregnancy and breast-feeding. stay on the safe side and avoid use.

hesperidin dosing for your reference

the following doses have been studied in scientific research: by mouth:

for the treatment of hemorrhoids inside the anus: 150 mg of hesperidin plus 1350 mg of diosmin twice daily for 4 days, followed by 100 mg of hesperidin and 900 mg of diosmin twice daily for 3 ays

for preventing the return of hemorrhoids inside the anus: 50 mg of hesperidin plus 450 mg of diosmin twice daily for 3 months.

for the treatment of leg ulcers caused by poor blood circulation (venous stasis ulcers): a combination of 100 mg of hesperidin and 900 mg of diosmin daily for up to 2 months.