Darunavir Manufacturer 206361-99-1 For Anti-AIDS CAS NO.206361-99-1

Min.Order Quantity:: 10 Gram

Purity:: 99%min

Port:: ShangHai

Payment Terms:: T/T,MoneyGram

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Keywords

99%min Darunavir
Darunavir Manufacturer
For Anti-AIDS

Quick Details

ProName: Darunavir Manufacturer 206361-99-1 For...
CasNo: 206361-99-1
Molecular Formula: C27H37N3O7S
Appearance: White Powder
Application: For Pharmaceutical Raw Materials
DeliveryTime: 2-4 days after confirmed your payments
PackAge: 100g/ bag, 2 kg/ bag, 25kg/ carton or ...
Port: ShangHai
ProductionCapacity: 1000 Metric Ton/Month
Purity: 99%min
Storage: Dry and cool place
Transportation: By DHL, TNT, FedEx, HKEMS, UPS, Etc
LimitNum: 10 Gram

Superiority

advantages:

hubei xinrunde chemical co., ltd is a renowned pharmaceutical manufacturer. we can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. never stop striving to offer our best service is our philosophy. we have flexible and untraceable payment terms. as a leading manufacture, our products have been exported to germany, norway, poland, finland, spain, uk, france, russia, usa, brazil, mexico, australia, japan, korea, thailand, indonesia, uruguay and many other countries.

1. quality.every batch of steroid powders have tobetested by our qc(quality control) before they are allowed to sell.

2 . delivery we have stock, so we can delivery quickly at the very day when receive the payment. within 24 hours after receiving the payment lead time 4 or 7 days.

3 . discreet package safelyand professionally disguised package guaranteed. for your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4 . warm after-sale service any of your question would be solved for the first as soon as possible.

Details

darunavir basic information

aids treatment

product name:	darunavir
synonyms:	[(1s,2r)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic acid (3r,3as,6ar)-hexahydrofuro[2,3-b]-furan-3-yl ester;darunavir;tmc-114;uic-94017;[(1s,2r)-3-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic acid (3r,3as,6ar)-hexahydrofuro[2,3-β]-furan-3-yl ester;[(3r,3as,6ar)-2,3,3a,4,5,6a-hexahydrofuro[5,4-b]furan-3-yl] n-[(2s,3r)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate;d03656;darunavir (usan/inn)
cas:	206361-99-1
mf:	c27h37n3o7s
mw:	547.66
einecs:	1592732-453-0
product categories:	antiviral agents;intermediates & fine chemicals;pharmaceuticals;aromatics;heterocycles;inhibitors;peptides
mol file:	206361-99-1.mol

darunavir chemical properties

melting point	74-760c
storage temp.	-20°c freezer

safety information

msds information

darunavir usage and synthesis

aids treatment	darunavir is a new kind of non peptide anti retroviral protease inhibitors in aids therapy. it is first developed by the johnson pharmaceutical iceland branch, tibotec. it is of the highest bioavailability in the 6 protease inhibitors (saquinavir, ritonavirvir, indinavir, naphthalene nelfinavir, amprenavir and abt378/r). it acts by blocking the formation of new and mature virus particles from the surface of the infected host cells and inhibiting the virus's protease. when the product is used for a long time, it usually can reduce the hiv virus vector in blood, increase the count of cd4 cells, reduce the chance of hiv infection, improve the quality of life and prolong life. it is suitable for adults who are infected with the hiv virus but have no effect on the use of existing antiretroviral drugs. the drug must be combined with the use of low doses of ritonavir or other antiretroviral agents, in order to improve the efficacy. the antiviral activity in vitro can be evaluated by being against acute and chronic infected lymphocytes and lymphocytes in peripheral blood. the ic50 is 0.012 to 0.08 mmol/ l for acute infected cells and 0.41 mmol/l for chronic infected cells. for oral administration, recommended dose is 1,200mg once and twice per day. the doseshould be reduced for patients with mild to moderate liver dysfunction and those with renal dysfunction. the adverse reaction of darunavir is mainly gastrointestinal reaction, flushing, itching and perioral numbness, depression, mood disorders, taste disorder etc. this product is not recommended for patients with moderate to severe liver dysfunction. because of the sulfonamides in this component, it is prohibited for those who are allergic to sulfanilamide and any component in the prescription of this product.
chemical properties	white amorphous solid
uses	second generation hiv-1-protease inhibitor; structurally similar to amprenavir. antiviral
definition	chebi: an n,n-disubstituted benzenesulfonamide bearing an unsubstituted amino group at the 4-position, used for the treatment of hiv infection. a second-generation hiv protease inhibitor, darunavir was designed to form robust interactions with the protease enzyme from many strains of hiv, including those from treatment-experienced patients with multiple resistance mutations to other protease inhibitors.