FASUDIL CAS NO.88-32-4

Min.Order Quantity:: 100 Gram

Purity:: 99%

Port:: Any Chinese main ports

Payment Terms:: L/C,D/A,D/P,T/T,Other

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Product Details

Keywords

at877
HIGH purity by own lab 35486-42-1
HA-1077：Eril

Quick Details

ProName: FASUDIL
CasNo: 88-32-4
Molecular Formula: C14H17N3O2S
Appearance: white to brown low melting crystallin...
Application: 35486-42-1
DeliveryTime: Within 7 working days since received y...
PackAge: 1g;5g;10g;25g;50g;100g;500g;1KG;5KG,25...
Port: Any Chinese main ports
ProductionCapacity: 100 Kilogram/Month
Purity: 99%
Storage: 2-8, cold storage, to avoid light stor...
Transportation: BY SEA /BY AIR /BY COURIER
LimitNum: 100 Gram
Heavy metal: NULL
Grade: Industrial Grade,Food Grade,Pharma Gra...
Valid Period: 6 month
Application: Multipurpose intermediate
Certification: ISO/9001 Certificate

Superiority

fasudil basic information

product name:	fasudil
synonyms:	fasudil;1-(5-isoquinoline-sulfonyl)-homopiperazine;at877;hexahydro-1-(5-isoquinolinylsulfonyl)-1h-4-diazepine;ha-1077 dihydrochloride novel vasodilato r age;ha 1077, dihydrochloride, 99+%;hexahydro-1-(5-isoquinolinylsulfonyl)-1h-1,4-diazepine;ha-1077：eril
cas:	103745-39-7
mf:	c14h17n3o2s
mw:	291.37
einecs:
product categories:	protein kinase inhibitors and activators;protein kinase;signalling;angiogenesis and metastasis;intracellular signaling;apis;eril
mol file:	103745-39-7.mol

fasudil chemical properties

storage temp.	store at rt
solubility	h₂o: >200 mg/ml
form	solid
color	white
cas database reference	103745-39-7(cas database reference)

safety information

wgk germany	3
rtecs	hm4031166

msds information

fasudil usage and synthesis

chemical properties	white crystalline solid
usage	vasodilator (cerebral), ca antagonist
usage	a potent calcium antagonist vasodilator which is considered to act by employing different mechanisms from the usual calcium channel blockers since it inhibits (1) calcium ionophore a23187 induced co ntraction in arterial strips and (2) phenylephrine induced contraction in calcium free media suggesting that its site of action is in the intracellular space. also reported to potently inhibit rho- associated kinase (rock ic50= 10.7 um).
biological activity	cyclic nucleotide-dependent protein kinase inhibitor and rho-associated kinase inhibitor (ic50 = 10.7 μm). ca2+ antagonist and vasodilator. also inhibits proliferation of vascular smooth muscle cells.

fasudil preparation products and raw materials

raw materials

isoquinoline

service we provide:

1. mixed container, we can mix different items in one container.

2. quality control, before shipment, free sample for test. after shipment, keep sample for 3 years

3. prompt shipment with professional documents

4. packing as your request, with photo before shipment

Details

exhibition in shanghai

we have clients throughout the world：

professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet your desire.

our laboratoy

we have our own independent lab test center：

this makes sure that our technology support is reliable and authoritative.all of self-owned fine chemicals are manufactured strictly in accordance with international standard.,and also has scientific cooperation with local colleges and institutes.