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Hubei God bull Pharmaceutical Co.,LtdGW-0742/GW0742 Sarms Powder for bodybuilding//www.lookchem.com/300w//2010/0625/317318-84-6.jpg
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GW-0742/GW0742 Sarms Powder for bodybuilding CAS NO.317318-84-6

Min.Order Quantity:
10 Gram
Purity:
99%
Port:
shenzhen hongkong
Payment Terms:
T/T,Western Union,MoneyGram

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Product Details

Keywords

  • GW-0742
  • GW0742
  • sarms

Quick Details

  • ProName: GW-0742/GW0742 Sarms Powder for bodyb...
  • CasNo: 317318-84-6
  • Molecular Formula: C21H17F4NO3S2
  • Appearance: white powder
  • Application: bodybuilding
  • DeliveryTime: within a week
  • PackAge: Discreet packing ways as your requirem...
  • Port: shenzhen hongkong
  • ProductionCapacity: Metric Ton/Day
  • Purity: 99%
  • Storage: Store in cool and dry area and keep aw...
  • Transportation: EMS DHL AND SO ON
  • LimitNum: 10 Gram

Superiority

Rich experience.

We have specialized in this field for 7 years. Our steroids and hormones have been exported to overseas, like Europe, Africa, Asia, America and other countries. And we have got very good feedback from our customers, and established long friendly relations of cooperation.

High quality products with the best price

1.All powders are factory directly supplying and have much in stock.

2.Before each powder send out, it all will be tested again by our technician, if the quality good, then it can be sent out to customers.

Professtional packing and fast delivery

1.Professtional team for packing, different country and quantity order have different packing way, sure package the products the best to your order.

2.We have mass stock, so that we can guarantee all the package can be sent out as soon as possible after you pay and should arrive your hands 3-7 days safely by DHL,TNT,FEDEX,HKEMS,UPS,etc.

Best pre-sell and after-sell service.

1.Once the package send out, tracking number and packing picture should email you later

2.For raw powder buyer, we also can help you cook steroid powder into injection and supply you all the things to make ready use injection, such as 10ml vials,0.22um-0.45um whatman filter,crimper machine and filter pump.

Customer feedback

Hi , package delivery and packed well , very satisfed with your service,wish cooperation with you again

—— Jason Davis

I am very very appreciate with the product quality , high purity and good appearance. wish you good business

—— Larry Owe

although some problems happens on the purchase , you show me a good attitude to resolve it and I got the product , good job

—— Terry Neal

Order Process :

1.

We talk with the order and total cost

2.

Client sends money and supply ship infomation

3.

We send package and supply track number

4.

Package delivery and after sold service

Details

Gw-0742 brief introduction

1. Name: GW-0742

2. Other Name: GW610742

3. CAS: 317318-84-6

4. Molecular Formula:C21H17F4NO3S2

5. Formula Weight:471.5

6. appearance:white solid

7. Mp:134.5-135.5 °C

8.Category:Sarm Steroid

GW-0742 Description:

1. GW0742 is a high affinity PPAR-β/δ agonist reduces lung inflammation induced by bleomycin instillation in mice.

2. A high throughput screening campaign was conducted to identify small molecules with the ability to inhibit

3. the interaction between the vitamin D receptor (VDR) and steroid receptor coactivator.

4. These inhibitors represent novel molecular probes to modulate gene regulation mediated by VDR. The peroxisome proliferator-activated receptor δ (PPARδ) agonist GW0742 was among the identified VDR-coactivator inhibitors and has been characterized herein as a pan nuclear receptor antagonist at concentrations higher than 12.1 µM.

5. The highest antagonist activity for GW0742 was found for VDR and the androgen receptor (AR). Surprisingly, GW0742 behaved as PPAR agonist/antagonist activating transcription at lower concentration and inhibiting this effect at higher concentrations.

6. A unique spectroscopic property of GW0742 was identified as well. In the presence of rhodamine-derived molecules, GW0742+ increased fluorescence intensity and fluorescence polarization at an excitation wavelength of 595 nm and emission wavelength of 615 nm in a dose dependent manner.

7. The GW0742-inhibited NR-coactivator binding resulted in a reduced expression of five different NR target genes in LNCaP cells in the presence of agonist. Especially VDR target genes CYP24A1, IGFBP-3 and TRPV6 were negatively regulated by GW0742.

8. GW0742 is the first VDR ligand inhibitor lacking the secosteroid structure of VDR ligand antagonists. Nevertheless, the VDR-meditated downstream process of cell differentiation was antagonized by GW0742 in HL-60 cells that were pretreated with the endogenous VDR agonist 1,25-dihydroxyvitamin D3.

There are two main uses with GW-0742.

1.The first and most common use is that of increased endurance. GW0742 has been banned for professional athletes due to the unfair advantage it provides to endurance athletes. Anyone want a drastic increase in endurance will find that GW truly shines in this aspect. It takes effect very quickly and the results can be staggering. A common dose of 10 mg day will provide a significant increase in endurance.

2.The second common usage with GW0742 is that of fat loss. Many users turn to GW as it has shown to melt off fat while still being non-catabolic. You will find that you can still hold on to some muscle as you are losing fat. It helps when you are running it in conjunction with SARMS Ostarine and S4, to hold on to as much muscle as possible. A dosage of 10 mg a day will provide good amounts of fat loss, but an increase to 20 mg a day will provide much more in this area.

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