USD $1,050.00-1,150.00 / Metric Ton
USD $8.20-8.80 / Kilogram
USD $4.50-5.00 / Liter
USD $2.00-10.00 / Kilogram
USD $1.00-89.00 / Kilogram
USD $2.00-10.00 / Kilogram
USD $2.00-10.00 / Kilogram
USD $2.00-10.00 / Kilogram
high quality
gefitinib basic information |
product name: | gefitinib |
synonyms: | iressa;gefitinib;akos 91371;n-(3-chloro-4-fluoro-phenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine;n-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine;zd 1839;4-quinazolinamine, n-(3-chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-;gefitinib(tinibs) |
cas: | 184475-35-2 |
mf: | c22h24clfn4o3 |
mw: | 446.9 |
einecs: | |
product categories: | active pharmaceutical ingredients;gefitinib;molecular targeted antineoplastic;intermediates & fine chemicals;pharmaceuticals;pharmaceutical intermediate;apis;iressa;anti-cancer&immunity;api |
mol file: | 184475-35-2.mol |
gefitinib chemical properties |
mp | 119-1200c |
storage temp. | store at rt |
cas database reference | 184475-35-2(cas database reference) |
safety information |
gefitinib usage and synthesis |
chemical properties | light-yellow crystalline powder |
usage | gefitinib (iressa, zd-1839) is an egfr inhibitor for tyr1173, tyr992, tyr1173 and tyr992 in the nr6wtegfr and nr6w cells with ic50 of 37 nm, 37nm, 26 nm and 57 nm, respectively. |
usage | gefitinib is an antineoplastic. |
biological activity | orally active, selective inhibitor of egfr tyrosine kinase (ic 50 = 23-79 nm). shows minimal activity against erbb2, kdr, c-flt, pkc, mek and erk-2. blocks egfr autophosphorylation and inhibits tumor growth in mice bearing a range of human xenografts. |
gefitinib preparation products and raw materials |