Good quality Tetracycline hydrochloride//64-75-5 CAS NO.64-75-5

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tetracycline hydrochloride 64-75-5

item	standard	result
characteristics	a white or yellowish white powder .odorless or almost.bygroscopic	conforms
identification	a:b:c the positive reaction.	conforms
solubility	very soluble in water, insoluble in acetone , chloroform, ether.	conforms
specific optical rotation	+53.5°~ +59.0°	+58.0°
acidity of alkalinity	5.0~7.5	6.7
impurity a	2%max	conforms
impurity c	3% ~15%	conforms
any other impurity	not more than the area of the principal peak	conforms
	in the chromatogram obtained with rs(b)5%
total other impurity	not more than 3times the area of the principal peak	conforms
	in the chromatogram obtained with rs(b)15%
disregard limit	ae of the principal peak in the chromatogram	conforms
	obtained with rs(c)1%
loss on drying (pct)	max8.0	5.0%
sulphate	27.0-31.0%	28.4%max
sulphated ash	1% max	0.2%
microcount limit test	nmt 500 col/g	10 col/g
microcount-yeast and molds	nmt 10 col/g	conforms
microcount-escherichia coli	absent	conforms
microcount-staphy lococcus aureus	absent	conforms
microcount-pseudo monas	absent
assay	≥680i.u./mg (dry)	687i.u./mg dry 653i.u./mg moist