USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
1. hubei jusheng technology co., ltd., is a global chemical industry manufacturers and suppliers of pharmaceuticals and intermediates in china.
2. the yearly production capacity is 50000mt, 80% for export.we have a professinal export team. both by air and by sea,we ensure that we meet the customer expectations with promptness.
3. our company facing global high-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and rare chemicals trade. corey have well-equipped machine, strong technical force and considerate marketing team service.
4. we also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.
detailed product description
rosiglitazone maleate
synonyms: 5-((4-[2-(methyl-2-pyridinylamino)-ethoxy]-phenyl)-methylene)-2,4-thiazolidinedione;5-{p-[2-(methyl-2-pyridylamino)ethoxy]benzyl}-2,4-thiazolidinedione maleate;rosiglitazone maleate;rosiglitazonetartrate;avandi;brl-49653c;rsiglitazonemaleate;5-(4-(2-(methyl(pyridin-2-yl)amino)ethoxy)benzyl)thiazolidine-2,4-dione maleate
cas: 155141-29-0
mf: c22h23n3o7s
mw: 473.5
chemical properties white to off-white solid
usage insulin sensitizer; binds to peroxisome proliferator activated receptor gamma (ppar- γ).
usage thiazole alkanes antidiabetic drug
package: 25kg/drum
standard: enterprise standard
lead time: within 24 hours after receiving the payment
delivery time:4-6 working days by air for quantity less than 200kgs or 20 days by sea for quantity over than 250kg.
certificates: iso9001
payment terms: , money gram, t/t
rosiglitazone is a thiazolidinedione insulin sensitizer that activates pparγ, decreasing blood glucose and insulin levels. rosiglitazone exhibits anti-diabetic, anti-inflammatory, antioxidative, anticancer, anti-angiogenic, antihypertensive, and anti-fibrotic activities. in vivo, rosiglitazone decreases lps-stimulated production of tnf-α, il-1β, and il-6 as well as activity of myeloperoxidase; it also inhibits activation of nf-κb, preventing mastitis. in multiple myeloma cells, rosiglitazone suppresses expression of hif-1α and igf-1, decreases activation of aky, and erk, and inhibits cell viability and proliferation. this compound also inhibits endothelin-1-induced vasoconstriction in a no-dependent manner in animal models of pulmonary arterial hypertension. additionally, rosiglitazone prevents activation of ap-1, production of collagen, and differentiation in fibroblasts.