High purity Thalidomide with best price and good quality CAS NO.50-35-1

product name:

thalidomide

synonyms:

(+/-)-2-(2,6-dioxo-3-piperidinyl)-1h-isoindole-1,3(2h)-dione;2-(2,6-dioxo-3-piperidinyl)-1h-iso-indole-1,3(2h)-dione;alpha-phthalimidoglutarimide;3-phthalimidoglutarimide;(+/-)-thalidomide;thalidomide;(+/-)-n-(2,6-dioxo-3-piperidinyl)phthalimide;n-(2,6-dioxo-3-piperidinyl)phthalimide

cas:

50-35-1

mf:

c13h10n2o4

mw:

258.23

product categories:

intermediates & fine chemicals;pharmaceuticals;api's;cytokine signaling;signalling;influenza viruses;angiogenesis and metastasis;inhibitor;roccal

mol file:

50-35-1.mol

chemical properties

melting point

269-271°c

boiling point

509.7 °c at 760 mmhg

density

1.503 g/cm3

flashing point

262.1 °c

vapor pressure

1.65e-10 mmhg at 25°c

storage temp.

store at rt

solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 0.6 mg/ml

water solubility

<0.1 g/100 ml at 22 ºc

stability

stable. combustible. incompatible with strong oxidizing agents.

quality index

water：

≤0.5%

microbial limits：

meets the requirements

heavey metals：

20ppm

single impurity：

≤0.1%

total impurities：

≤0.3%

content：

98-101.5%

conclusion：

usp31

usage and synthesis

chemical properties

white powder

usage

antiinfective (topical)

inhibits fgf-induced angiogenesis. inhibits replication of human immunodeficiency virus type 1. teratogenic sedative. there is now a growing clinical interest in thalidomide, and it is introduced as an immunomodulatory agent used primarily in combination with dexamethasone to treat multiple myeloma.

air & water reactions

insoluble in water.

fire hazard

flash point data for thalidomide are not available; however, thalidomide is probably combustible.

biological activity

teratogen, sedative-hypnotic with inherent anti-inflammatory properties. a selective inhibitor of tumor necrosis factor α (tnf- α ) synthesis.