cefprozil

molecular formula：c18h19n3o5s·h2o

molecular weight：407.44

cas：121123-17-9

5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[amino(4-

hydroxyphenyl)acetyl]amino]-8-oxo-3-(1-propenyl)-,

(6r,7r)-7-[(r)-2-amino-2-(p-hydroxyphenyl)acetamido]-8-oxo-3-propenyl-5

-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic [121123-17-9].

cefprozil contains not less than 900µg and not more than 1050µg of

cefprozil (c18h19n3o5s)per mg,calculated on the anhydrous basis.

anhydrous 389.43 [92665-29-7].

ph：between 3.5and 6.5,in a solution containing 5mg per ml.

water,method：not less than 3.5%and not more than 6.5%.

cefprozil (e)-isomer ratio— calculate the ratio of the cefprozil (e)-

isomer to the total cefprozil taken by the formula：e/(e+z),

in which eis the content of cefprozil (e)-isomer,in µg per mg,as

determined in the assay,and zis the content of cefprozil (z)-isomer,in µ

g per mg,as determined in the assay:the ratio is between 0.06and 0.11.

appearance：white to light yellow powder

cefadroxil：not more than 0.5%

other single impurity：not more than 0.5%

other impurities total：not more than 1.5%

ethylene glycol：not more than 0.062%

dmf：not more than 0.088%

residue on ignition：not more than 0.1%

heavy metal：not more than 20ppm