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Irbesartan CAS NO.138402-11-6

FOB Price:
USD 1.00-1.00 /Metric Ton Get Latest Price
Min.Order Quantity:
1 Metric Ton
Purity:
99%min
Port:
Shanghai
Payment Terms:
L/C,T/T,

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Product Details

Keywords

  • 138402-11-6
  • Irbesartan (GMP)
  • 138402-11-6 Irbesartan

Quick Details

  • ProName: Irbesartan
  • CasNo: 138402-11-6
  • Molecular Formula: C25H28N6O
  • Appearance: POWDER
  • Application: Cardiovascular Drug; Antihypertensive,...
  • DeliveryTime: 10day
  • PackAge: 25 kg /drum,1kg/bag
  • Port: Shanghai
  • ProductionCapacity: 2000 Metric Ton/Quarter
  • Purity: 99%min
  • Storage: RT
  • Transportation: by sea,by air
  • LimitNum: 1 Metric Ton
  • Related Substances: 0.1
  • Residue on Ignition: 0.1
  • Heavy Metal: 10PPM
  • Valid Period: 12m

Superiority

olmesartan medoxomil has excellent antihypertensive effect. seven placebo-controlled clinical studies showed that olmesartan medoxomil has a potent antihypertensive effect with daily doses of 5 mg, 20 mg and 40 mg reducing the systolic blood pressure by 12.4 mmhg, 15.1 mmhg and 17.6 mmhg, respectively ; reduced sitting diastolic blood pressure 9.8 mmhg, 12.2 mmhg and 13.1 mmhg

the antihypertensive effect of olmesartan medoxomil has no significant difference in patients of different genders and ages (<65 years or ≥65 years). the recommended initial dose of olmesartan medoxomil in the united states is 20 mg / day, with an additional 40 mg / day if necessary. the investigators looked at the antihypertensive effect of olmesartan medoxomil 20 mg qd, and ambulatory blood pressure monitoring at 24 hours showed that this dose reduced average systolic blood pressure by 15.2 mm hg and mean diastolic blood pressure by 11.2 mm hg, the same as olmesartan medoxomil 10 mg bid , were significantly better than placebo. and at each observation time point of blood pressure are more significant, the degree of similar decline. clinical observations fully confirmed, oral olmesartan medoxomil once a day for 24 hours to control blood pressure

Details

cas registry number 138402-11-6
molecular structure 138402-11-6 irbesartan
density 1.3g/cm3
melting point 180-181℃
boiling point 648.6°c at 760 mmhg
refractive index 1.689
flash point 346°c
vapour pressur 1.05e-16mmhg at 25°c

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