China (Mainland) 
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name: |
kaempferol |
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synonym: |
c.i. 75640; kaempferol; 3,5,7,4-tetrahydroxyflavone; 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4h-chromen-4-one; 2-(2,4-dihydroxyphenyl)-5,7-dihydroxy-4h-chromen-4-one |
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cas no: |
520-18-3 |
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appearance: |
light yellow needle crystal |
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molecular formula: |
c15h10o6 |
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molecular weight: |
286.23 |
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herb sourse: |
fruit of sophora japonica l. |
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content: |
98% |
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assay method: |
hplc |
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specification: |
90%,95%,98% by hplc |
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melting point: |
276~278°c |
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certificate of analysis
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item |
specification |
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description: appearance odor particle size bulk density extract solvents |
purple -red fine powder characteristic 100% pass through 80 mesh sieve 45.0g/100ml~55.0 g/100ml water |
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identification color reaction |
positive reaction |
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tests: loss on drying(5h at 105°c) ash(3h at 600°c) heavy metals(as pb) arsenic(as as2o3) residual solvents |
<5.0% <5.0% <10ppm <1ppm eur. pharm. 2000 |
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assay: kaempferol |
98%
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microbial: total bacterial count yeast & mould escherichia coli presence salmonella staphylococcus |
max.1000cfu/g max.100cfu /g negative negative negative |
functions and applications
1. kaempferol was found to be active in promoting opossum kidney cell growth . kaempferol stimulates kidney cells proliferation and increases secretion of bone growth factor . kaempferol may serve to stimulate kidney repair and up-regulate bone formation and may be useful in treating chronic kidney disease and osteoporosis .
2. kaempferol can inhibit the apoptosis induced by h202 in neonatal rat cardionyocytes . the protective effects could be related to their antiocidant activity and its ability to regulate the expression of bcl-2 , bax ,caspase-3 protein .
3. kaempferol is a blocker of voltagegated potassium channels in pyramidal neurons of rat hippocampus . the electrophysiological effects of kaempferol may be one mechanism of its protective effects on rat hippocampal neurons in acutely transient hypoxia .
4. kaempferol owe to the strong antioxidant properties , can scavenge superfluous superoxide free radicals in human body , preventing dna and cells from oxidative damage . it show pharmacological effects in anti-tumour ,anti-inflammation and anti-senility ,etc.
5. kaempferol has the effect of anti-epilepsy , antispasmodic ,anthelone , antiulcer ,choleretic, diuretic activity and relieving cough .
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package: packed in paper-drums and two plastic-bags inside. 25kg per drum or according to the needs of customers. net weight: 25kgs/drum. i.d. 40cmx50cm
storage: stored in a clean, cool, dry area; keep away from strong, direct light.
shelf life: two years when properly stored.