the nature of lacidipine
m.p. 174-175 ° c
storage conditions -20 c freezer
solubility dmso: soluble20mg / ml, clear
color white to beige
merck 14,5331
cas database 103890-78-4 (cas database reference)
laxidipine use and synthesis method
chemical properties in ethyl acetate crystallization, melting point 174 ~ 175 ℃.
use of vascular selective calcium antagonists, with high efficiency and long-lasting antihypertensive activity. for high blood pressure.
use for the treatment of hypertension
production methods o-phthalaldehyde and tert-butyl triphenylphosphine acetate in dichloromethane, at 0 ° c for 15min, tert-butyl 3- (2-formylphenyl) acrylate. and then 2-amino-2-butenoate, in acetic acid, at room temperature for 5h derived.