Mecobalamin CAS NO.13422-55-4

methylcobalamin (mecobalamin, mecbl, or meb₁₂) is a cobalamin, a form of vitamin b₁₂. it differs from cyanocobalamin in that the cyanide is replaced by a methyl group.^[1] methylcobalamin features an octahedral cobalt(iii) centre. methylcobalamin can be obtained as bright red crystals.^[2] from the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal-alkyl bonds. nickel-methyl intermediates have been proposed for the final step of methanogenesis.

methylcobalamin is equivalent physiologically to vitamin b₁₂, and can be used to prevent or treat pathology arising from a lack of vitamin b₁₂ (vitamin b12 deficiency), such as pernicious anemia.

methylcobalamin is also used in the treatment of peripheral neuropathy,diabetic neuropathy, and as a preliminary treatment for amyotrophic lateral sclerosis.