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Offer CAS.NO: 1508-75-4 CAS NO.1508-75-4

FOB Price:
USD 1.00-1.00 /Kilogram Get Latest Price
Min.Order Quantity:
1 Kilogram
Purity:
99%
Port:
China main ports
Payment Terms:
L/C,T/T,MoneyGram,Other

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  • 1508-75-4
  • 1508-75-4
  • 1508-75-4

Quick Details

  • ProName: Offer CAS.NO: 1508-75-4
  • CasNo: 1508-75-4
  • Molecular Formula: C17H20N2O2
  • Appearance: white crystalline powder
  • Application: 1508-75-4
  • DeliveryTime: Promopt .
  • PackAge: 1g;5g;10g;25g;50g;100g;500g;1KG;5KG,25...
  • Port: China main ports
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 99%
  • Storage: 2-8, cold storage, to avoid light stor...
  • Transportation: by air /by sea /by courie r
  • LimitNum: 1 Kilogram
  • Valid Period: 6 month
  • Application: Multipurpose intermediate
  • Certification: ISO/9001 Certificate

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2. material safety data sheet (msds)

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tropicamide basic information
ophthalmic drugs application
product name: tropicamide
synonyms: benzeneacetamide, n-ethyl-alpha-(hydroxymethyl)-n-(4-pyridinylmethyl)-;bistropamide;component of paremyd;epitromina;mydriacyl;mydriat;mydrin;mydrum
cas: 1508-75-4
mf: c17h20n2o2
mw: 284.35
einecs: 216-140-2
product categories: aromatic carboxylic acids, amides, anilides, anhydrides & salts;heterocyclic compounds;heterocycles;intermediates & fine chemicals;pharmaceuticals;acetylcholine receptor;inhibitors
mol file: 1508-75-4.mol
tropicamide structure
tropicamide chemical properties
mp 98 °c
storage temp. 2-8°c
solubility 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/ml
form solid
color white
merck 9780
cas database reference 1508-75-4(cas database reference)
nist chemistry reference tropicamide(1508-75-4)
safety information
hazard codes xn,xi
risk statements 20/21/22-36/37/38-42/43-41-37/38-22
safety statements 22-26-36-36/37/39
wgk germany 3
rtecs cy1487860
msds information
tropicamide usage and synthesis
ophthalmic drugs tropicamide is an anticholinergic agent. at room temperature, it is a white crystalline powder and is odorless. it is slightly soluble in water and easily soluble in ethanol, dilute hydrochloric acid, sulfuric acid and chloroform. it can block the excitement of iris sphincter and ciliary muscle induced by acetylcholine. its 0.5% solution can cause mydriasis while its 1% solution can cause ciliary muscle paralysis and mydriasis. clinically it is mainly used for the treatment of eye drops mydriasis and paralysis.
tropicamide is the synthetic derivative of tropic acid. it has a relative low dissociation constant with good intraocular permeability and strong tissue diffusion capability which may be the underlying mechanism for its quick onset but short maintaining time. after the drop of the 0.5% or 1% solution of this product, the instillation dilation and paralysis adjustment can reach peak within 20-30 minutes. then the effect gradually decreases with adjusting paralysis (residual) for 2 to 6 hours and mydriasis (residual) for about 7 hours. tropicamide is similar drug as atropine which can cause a dramatic increase on the angle closure glaucoma intraocular pressure as well as possibly stimulate undiagnosed angle-closure glaucoma.
the potency of ciliary muscle paralysis adjustment of tropicamide eye drops is closely related with the doses used, its 0.25%, 0.5%, 0.75% and 1% four concentrations can all adjust paralysis. after instillation, the maximum degree of residual adjustment is 0.25%: diopter: 3.17; 1% diopter: 3.17. the residue adjustment degree can be maintained in cases of the refraction being 2.0 or less, 0.75% and 1% solutions can maintain for 40 minutes while 0.5% can only maintain about 15 minutes. after a drop of 1% solution, have the second drop after 5 to 25 minutes and by doing this, we can get more satisfactory ciliary muscle paralysis effect for about 20 to 30 minutes. after 2 to 6 hours, you can read books and newspapers with the adjustment function being able to recover to the level before drop within 6 hours.
the above information is edited by the chemicalbook of dai xiongfeng.
application it can be used as an anti-cholinergic drugs or mydriatic drug.
it is a kind of m4 muscarinic acetylcholine receptor antagonist.
chemical properties crystalline solid
usage antidepressant, nutrient; ld50(rat) 1634 mg/kg ip
usage indicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye.
usage ophthalmic anticholinergic. mydriatic
biological activity m 4 selective muscarinic receptor antagonist.

hennan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.

Details

tropicamide basic information
ophthalmic drugs application
product name: tropicamide
synonyms: benzeneacetamide, n-ethyl-alpha-(hydroxymethyl)-n-(4-pyridinylmethyl)-;bistropamide;component of paremyd;epitromina;mydriacyl;mydriat;mydrin;mydrum
cas: 1508-75-4
mf: c17h20n2o2
mw: 284.35
einecs: 216-140-2
product categories: aromatic carboxylic acids, amides, anilides, anhydrides & salts;heterocyclic compounds;heterocycles;intermediates & fine chemicals;pharmaceuticals;acetylcholine receptor;inhibitors
mol file: 1508-75-4.mol
tropicamide structure
tropicamide chemical properties
mp 98 °c
storage temp. 2-8°c
solubility 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/ml
form solid
color white
merck 9780
cas database reference 1508-75-4(cas database reference)
nist chemistry reference tropicamide(1508-75-4)
safety information
hazard codes xn,xi
risk statements 20/21/22-36/37/38-42/43-41-37/38-22
safety statements 22-26-36-36/37/39
wgk germany 3
rtecs cy1487860
msds information
tropicamide usage and synthesis
ophthalmic drugs tropicamide is an anticholinergic agent. at room temperature, it is a white crystalline powder and is odorless. it is slightly soluble in water and easily soluble in ethanol, dilute hydrochloric acid, sulfuric acid and chloroform. it can block the excitement of iris sphincter and ciliary muscle induced by acetylcholine. its 0.5% solution can cause mydriasis while its 1% solution can cause ciliary muscle paralysis and mydriasis. clinically it is mainly used for the treatment of eye drops mydriasis and paralysis.
tropicamide is the synthetic derivative of tropic acid. it has a relative low dissociation constant with good intraocular permeability and strong tissue diffusion capability which may be the underlying mechanism for its quick onset but short maintaining time. after the drop of the 0.5% or 1% solution of this product, the instillation dilation and paralysis adjustment can reach peak within 20-30 minutes. then the effect gradually decreases with adjusting paralysis (residual) for 2 to 6 hours and mydriasis (residual) for about 7 hours. tropicamide is similar drug as atropine which can cause a dramatic increase on the angle closure glaucoma intraocular pressure as well as possibly stimulate undiagnosed angle-closure glaucoma.
the potency of ciliary muscle paralysis adjustment of tropicamide eye drops is closely related with the doses used, its 0.25%, 0.5%, 0.75% and 1% four concentrations can all adjust paralysis. after instillation, the maximum degree of residual adjustment is 0.25%: diopter: 3.17; 1% diopter: 3.17. the residue adjustment degree can be maintained in cases of the refraction being 2.0 or less, 0.75% and 1% solutions can maintain for 40 minutes while 0.5% can only maintain about 15 minutes. after a drop of 1% solution, have the second drop after 5 to 25 minutes and by doing this, we can get more satisfactory ciliary muscle paralysis effect for about 20 to 30 minutes. after 2 to 6 hours, you can read books and newspapers with the adjustment function being able to recover to the level before drop within 6 hours.
the above information is edited by the chemicalbook of dai xiongfeng.
application it can be used as an anti-cholinergic drugs or mydriatic drug.
it is a kind of m4 muscarinic acetylcholine receptor antagonist.
chemical properties crystalline solid
usage antidepressant, nutrient; ld50(rat) 1634 mg/kg ip
usage indicated to induce mydriasis (dilation of the pupil) and cycloplegia (paralysis of the ciliary muscle of the eye) in diagnostic procedures, such as measurement of refractive errors and examination of the fundus of the eye.
usage ophthalmic anticholinergic. mydriatic
biological activity m 4 selective muscarinic receptor antagonist.

hennan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion, the com[any was established in june. 1998 , until now having more than 18 years experience in manufacturing & exporting chemical raw material .
sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others . these products have been being well exported to europe , southeast asia , the middle east , africa , south america and some other countries and areas.

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