USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $9.00-99.00 / Kilogram
USD $100.00-150.00 / Kilogram
pentamidine isethionate basic information |
product name: | pentamidine isethionate |
synonyms: | 1,5-bis(p-amidinophenoxy)pentane bis(2-hydroxyethanesulfonate salt);1,5-bis[p-amidinophenoxy]pentane bis[2-hydroxyethanesulfonate salt] isethionate salt;4,4'-(pentamethylenedioxy)dibenzamide bis(2-hydroxyethanesulfonate);4,4'-(pentamethylenedioxy)dibenzamidine, bis-2-hydroxyethanesulfonate;pentamidine isethionate;pentamidine isethionate salt;4,4'-(pentamethylenedioxy)dibenzamidine bis(2-hyd;pentamidine isetionate |
cas: | 140-64-7 |
mf: | c23h36n4o10s2 |
mw: | 592.68 |
einecs: | 205-424-1 |
product categories: | api;hiv/aids/related products;amines;aromatics;intermediates & fine chemicals;pharmaceuticals |
mol file: | 140-64-7.mol |
pentamidine isethionate chemical properties |
mp | 188-194 °c(lit.) |
storage temp. | −20°c |
form | powder |
merck | 13,7192 |
cas database reference | 140-64-7(cas database reference) |
epa substance registry system | ethanesulfonic acid, 2-hydroxy-, compd. with 4,4'-[1,5-pentanediylbis( oxy)]bis[benzenecarboximidamide] (2:1)(140-64-7) |
safety information |
hazard codes | xi |
risk statements | 36/37/38-43 |
safety statements | 26-36/37 |
ridadr | 3249 |
wgk germany | 3 |
rtecs | cv6500000 |
hazardclass | 6.1(b) |
packinggroup | iii |
pentamidine isethionate usage and synthesis |
usage | has been widely used as a drug to treat protozoal diseases, such as malaria, amoebic dysentery and trypanosomiasis. it has also been shown to be effective for both prophylaxis of pneumocystic carinii pneumonia (pcc). |
usage | antiparasitic |
general description | odorless white or almost white crystals or powder. odor also reported as a slight butyric odor. very bitter taste. ph (5% aqueous solution) 4.5-6.5. |
air & water reactions | hygroscopic. may be sensitive to prolonged exposure to air. aqueous solutions deteriorate on storage. water soluble. |
reactivity profile | can decompose on prolonged exposure to light. |
fire hazard | flash point data for pentamidine isethionate are not available; however, pentamidine isethionate is probably combustible. |
biological activity | antimicrobial. neuroprotective; inhibits constitutive nitric oxide synthase in the brain and acts as a nmda glutamate receptor antagonist. |
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