China (Mainland) 
quick detail:
| product name: | ponazuril |
| alias: | toltrazuril sulfone |
| chemical name: | 1-methyl-3-[3-methyl-4-[4-(trifluoromethylsulfonyl)phenoxy]phenyl]-1,3,5-triazinane-2,4,6-trione |
| structural formula: |
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| molecular formula: | c18h14f3n3o6s |
| molecular weight: | 457.38000 |
| appearance: | white crystelline powder |
| packing: | 25kg/cardboard drum; 36.5 h47cm |
| cas no.: | 69004-04-2 |
specification of ponazuril:
| items | specifications | results |
| character | white or almost white crystalline powder;odorless | white crystelline powder, odorless |
| melting point | 242~246°c | 243.4~244.3°c |
| identification | 1) ir spectra is consistent with crs | complies |
| 2) the retention time of the major peak in the chromatogram of the assay preparation corresponds to that in the chromatogram of the standard preparation, as obtained in the assay | complies | |
| appearance of solution | colorless and clear liquid | colorless and clear liquid |
| related substances | individual impurity≤1.0% | 0.24% |
| total impuirties ≤2.0% | 0.70% | |
| loss on ignition | ≤0.5% | 0.32% |
| residue on ignition | ≤0.1% | 0.05% |
| heavy metals | not more than 10 parts per million | less than 10 parts per million |
| assay | not less than 98.0% of c18h14f3n3o6s(on dried basis) | 99.40% |
| conclusion: | complies with ponazuril enterprise standard | |
usage for ponazuril:
1) ponazuril is a drug currently approved for the treatment of equine protozoal myeloencephalitis in horses, caused by sarcocystis neurona.
2) veterinarians have been preparing a formulary version of the medication for use in small animals such as cats and
dogs against coccidia, an intestinal parasite. coccidia treatment is far shorter than treatment for epm.
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