Prucalopride 99% CAS NO.179474-81-8

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Min.Order Quantity:: 10 Gram

Purity:: ≧99.5%

Port:: Qingdao,China

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ProName: Prucalopride 99%
CasNo: 179474-81-8
Molecular Formula: C18H26ClN3O3
Appearance: white powder
Application: used for research
DeliveryTime: Within 3-7 days after receipt of your ...
PackAge: As customer request
Port: Qingdao,China
ProductionCapacity: 100 Metric Ton/Day
Purity: ≧99.5%
Storage: Store in a cool,dry place and keep awa...
Transportation: Common products:Sea/Air/Courier Dange...
LimitNum: 10 Gram
Moisture Content: 4.0~6.0%
Impurity: ≦0.6%
Single impurity: ≦0.1%
Methanol: Methanol

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product name :prucalopride

cas number: 179474-81-8
other name:r 093877;r093877;resolor;unii-0a09iuw5tp;prucalopride(r-93877)

prucalopride(179474-81-8)was a highly selective serotonin receptor agonist which could improve bowel functions,

including number of bowel movements and a range of other constipation symptoms,as well as health-related quality of life and patient satisfaction.the most common adverse events were headache,diarrhoea,nausea,abdominal pain,etc

Details

prucalopride

product name :prucalopride
structure
cas number: 179474-81-8
molecular formula c18h26cln3o3
molecular weight 367.874
batch no. 201711002

prucalopride(179474-81-8)was a highly selective serotonin receptor agonist which could improve bowel functions,

mete-analysis showed that the efficacy rate was significantly higher in prucalopride(179474-81-8)group （29.2%） than in the placebo group （12.6%, rr=2.37, 95% ci 2.02-2.79, p〈0.001）, while it was similar to that of peg 3350＋electrolytes group. the incidence rates of headache, dizziness, diarrhea, abdominal pain, and nausea were higher in the prucalopride group than in the placebo group （p≤ 0.05）. there were no differences in the incidence of flatulence and prolonged q t interval between the two groups （p〉0.05）. conclusion prucalopride is effective in the treatment of cc, with relatively milder and lower incidence of adverse reaction, and it could be a new choice for the treatment of cc.

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characteristics white to off-white powder
water 4.0~6.0%
melting point 100~110
single impurity ≦0.1%
purity ≧99.5%
solvent residue methanol≦0.3%, ethyl alcohol≦0.5% ,thf≦0.072%