Sorafenib CAS NO.284461-73-0

FOB Price:: USD 7.00-7.00 /Gram Get Latest Price

Min.Order Quantity:: 100 Gram

Purity:: 98% min

Port:: Qingdao,China

Payment Terms:: L/C,T/T,MoneyGram,Other

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284461-73-0
Sorafenib
98% Sorafenib

Quick Details

ProName: Sorafenib
CasNo: 284461-73-0
Molecular Formula: C21H16ClF3N4O3
Appearance: C21H16ClF3N4O3
Application: Used for research and industrial manuf...
DeliveryTime: Within7-10 days after receipt of your ...
PackAge: As customer request
Port: Qingdao,China
ProductionCapacity: 100 Kilogram/Month
Purity: 98% min
Storage: 3 years -20°C powder; 2 years -80°C in...
Transportation: Common products:Sea/Air/Courier ...
LimitNum: 100 Gram

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lorcaserin(856681-05-5)is an orally administered agent and a selective 5-ht2c receptor agonist for the treatment of obesity. it had been approved for marketing in us by fda on 27 june in 2012. in clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.

Details

molecular weight	464.83
formula	c₂₁h₁₆clf₃n₄o₃
cas number	284461-73-0
solubility	dmso: 63 mg/ml warmed (135.53 mm)
storage	3 years -20°c powder; 2 years -80°c in solvent;
remark	for obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.stock solution can be stored below -20 ℃ for several month.

sorafenib (rinn), marketed as nexavar by bayer, is a drug approved for the treatment of advanced renal cell carcinoma (primary kidney cancer). it has also received "fast track" designation by the fda for the treatment of advanced hepatocellular carcinoma (primary liver cancer), and has since performed well in phase iii trials. sorafenib is a small molecular inhibitor of raf kinase, pdgf (platelet-derived growth factor), vegf receptor 2 & 3 kinases and c kit the receptor for stem cell factor. a growing number of drugs target most of these pathways. the originality of sorafenib lays in its simultaneous targeting of the raf/mek/erk pathway.

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