Sulindac CAS NO.38194-50-2

properties
sulindac is a kind of yellow crystalline powder , with melting point 182-185 ℃, it is a non-steroidal anti-inflammatory drug. sulindac reduces the level and activity of several cyclin-dependent kinases (cdks) and induces apoptosis. sulindac metabolizes to sulindac sulfide (sc-200118), a cox (cyclooxygenase) inhibitor that represses ras signaling, and sulindac sulfone (sc-200120), an antitumor agent. sulindac is an inhibitor of cox-1 and cox-2. it can be used as anti-inflammatory analgesic

specification
index name spec
appearance yellow crystalline powder
melting point, ℃ 182-185
loss on drying,% ≤0.5
residue on ignition, % ≤0.1
heavy metals ≤10ppm
chromatographic purity,% ≤1.0
organic volatile impurity chloroform≤500ppm

application
1)used for rheumatoid arthritis, arm and knee arthritis, ankylosing spondylitis, slippery bursa phlogistic, and acute gout, etc.
2)used as anti-inflammatory analgesic