Supply 99% Afatinib/ BIBW 2992 CAS NO.439081-18-2

Min.Order Quantity:: 1 Gram

Purity:: 99%

Port:: HK, Shanghai, Shenzhen

Payment Terms:: T/T,MoneyGram

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Product Details

Keywords

Afatinib
BIBW 2992
BIBW2992

Quick Details

ProName: Supply 99% Afatinib/ BIBW 2992
CasNo: 439081-18-2
Molecular Formula: C24H25N5O3FCl
Appearance: white powder
Application: used by athletes to assist in training...
DeliveryTime: immediately
PackAge: aluminum foil bag
Port: HK, Shanghai, Shenzhen
ProductionCapacity: 100 Kilogram/Month
Purity: 99%
Storage: cool and dry place
Transportation: EMS,DHL,HK post,EUB,ETK,NL post,German...
LimitNum: 1 Gram

Superiority

1.high quality:

quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china and produce sarms in bulk quantity. we have 8 years experience making all kinds of sarms. and all our old customers throughout the world have very positive feedbacks towards our sarms. purity is all guaranteed over 98%. hplc and nmr is available if needed.

2.reasonable price:

we provide high quality products with competitive price in china. all customers are welcomed to send us inquiries and get quotation.

3.low moq:

no worry about the low moq, our moq is 1 gram or even lower.

4.good service.

fast response. we promise to reply within 24 hours including holidays and send quotation sheet and other documents within 48 hours.

before making orders, we do not cheat customers in order to get orders.

after selling, we promise to be reponsible and so not disappear if there is any complaint from customers on either our products or services.

5. fast shipping and secure courier.

we promise to send out products and provide tracking number within 3 working days. and we send via different couriers based on different destination countries. we usually use nl post, hk post, germany post, eub, etk, etc.

6.about resending or refunding if there is any loss of packages or failure to getting through custom.

we promise to resend up to half if it happens unluckily.

Details

afatinib is a new generation of oral small molecule tyrosine kinase inhibitor (tki) and is the first irreversible erbb family blocker that acts on the entire erbb family, including egfr. unlike the first-generation reversible egfr tki, afatinib binds irreversibly to egfr, thereby shutting down the cancer cell signaling pathway and inhibiting tumor growth.

product name	afatinib (bibw 2992)	cas number	39081-18-2
moculer formula	c24h25n5o3fcl	moculer weigh	485.944
appearance and traits	white powder	density	1.380g/cm3
melting point	100 - 102 °c	boiling point	676.917 at 760 mmhg
flash point	363.186°c	refractive index	1.668

afatinib (bibw2992) irreversibly inhibits egfr/her2 including egfr(wt), egfr(l858r), egfr(l858r/t790m) and her2 with ic50 of 0.5 nm, 0.4 nm, 10 nm and 14 nm in cell-free assays, respectively. afatinib (bibw 2992) is the second-generation potent and irreversible dual inhibitor of the epidermal growth factor receptor (egfr) and human epidermal growth factor receptor 2 (her2) tyrosine kinase.

1 local advanced or metastatic non-small cell lung cancer (nsclc) with epidermal growth factor receptor (egfr) gene-sensitive mutations, previously untreated with egfr tyrosine kinase inhibitor (tki)
2 local advanced or metastatic squamous type of non-small cell lung cancer (nsclc) with or without disease progression during platinum chemotherapy.