TIANFU-CHEM - 7-Ethyl-10-hydroxycamptothecin CAS NO.86639-52-3

Min.Order Quantity:: 1 Kilogram

Purity:: 99%

Port:: Shanghai

Payment Terms:: L/C,D/A,D/P,T/T,MoneyGram,Other

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Product Details

Keywords

7-Ethyl-10-hydroxycamptothecin
86639-52-3
C22H20N2O5

Quick Details

ProName: TIANFU-CHEM - 7-Ethyl-10-hydroxycampto...
CasNo: 86639-52-3
Molecular Formula: C22H20N2O5
Appearance: Light-Yellow Solid
Application: Organic synthesis
DeliveryTime: Prompt
PackAge: IN 25kg drums
Port: Shanghai
ProductionCapacity: 10 Metric Ton/Month
Purity: 99%
Storage: room tempurature
Transportation: As per the MSDS
LimitNum: 1 Kilogram
Heavy metal: N/A
Grade: Industrial Grade,Food Grade,Pharma Gra...
N/A: N/A

Superiority

our company engages in sodium tripolyphosphate (stpp) and sodium hexametabphosphate (shmp) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals imp&exp trading business. the company is located in zhengzhou high-tech development zone with import and export license. we passed iso 9001:2008 in 2009, and won "high-tech enterprise" by provincial government in 2013. our stpp and shmp has reached an annual output of 30000 tons and has successfully passed sgs, ciq audits on many occasions.

in 2011 we entered the fine chemical market of noble metal catalyst ,organic phosphine ligands and oled intermediates.with the joint efforts of our senior experts and professional technicians, tianfu has developed more than 500 compounds, which are widely used in the fields of production and life science. the objective of the company is to put quality first and put our customer’s needs first - the satisfaction of our customers is the company's ultimate goal. improving product quality and service level is our responsibility, and creating more value for our customer’s is our purpose. we are constantly striving to make henan tianfu a leading chemical supplier, and hope to create a better future with you.

Details

7-ethyl-10-hydroxycamptothecin basic information

product name:	7-ethyl-10-hydroxycamptothecin
synonyms:	camptothecin, 7-ethyl-10-hydroxy;4,11-diethyl-4,9-dihydroxy-1h-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4h,12h)-dione;7-ethyl-10-hydroxycamptothecin;7-ethyl-10-hydroxycamptothecine;7-ethyl-10-hydroxy-cpt;sn38;10-dihydroxy-;4’:6,7)indolizino(1,2-b)quinoline-3,14(4h,12h)-dione,4,7-diethyl-1h-pyrano(3
cas:	86639-52-3
mf:	c22h20n2o5
mw:	392.4
einecs:
product categories:	pharmaceutical raw materials;miscellaneous natural products;antitumors for research and experimental use;biochemistry;natural plant extract;chiral reagents;intermediates & fine chemicals;metabolites & impurities;pharmaceuticals;natural anti-cancer medical materials and it's derivatives;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from chinese medicinal herbs (tcm).;standardized herbal extract;chiral reagents, metabolites & impurities, pharmaceuticals, intermediates & fine chemicals;inhibitors
mol file:	86639-52-3.mol

7-ethyl-10-hydroxycamptothecin chemical properties

mp	217 °c
refractive index	21.5 ° (c=0.2, thf)
storage temp.	−20°c
cas database reference	86639-52-3(cas database reference)

safety information

hazard codes	t
risk statements	25
safety statements	45
rtecs	uq0491000

msds information

7-ethyl-10-hydroxycamptothecin usage and synthesis

chemical properties	light-yellow solid
usage	a metabolite of irinotecan, a dna topoisomerase inhibitor
biological activity	active metabolite of cpt-11 that inhibits dna topoisomerase i (ic 50 values are 0.74 and 1.9 μ m in p388 and ehrlich cells respectively). inhibits dna and rna synthesis (ic 50 values are 0.077 and 1.3 μ m respectively) but does not affect protein synthesis. displays potent antitumor activity against a range of human tumor cell lines (ic 50 values are 3.3, 13, 19 and 22 nm for hct-116, bel-7402, hl60 and hela cells respectively).