product name: oxfendazole
synonyms: [5-(phenylsulfinyl)-1h-benzimidazol-2-yl]carbamic acid methyl ester;loditac;oxfendazole;(5-(phenylsulfinyl)-1h-benzimidazol-2-yl)-carbamicacimethylester;5-(phenylsulfinyl)-2-benzimidazolecarbamicacidmethylester;5-(phenylsulfinyl)-2-benzimidazolecarbamicacimethylester;5-phenylsulfinyl-2-carbomethoxyaminobenzimidazole;hoe8105
cas: 53716-50-0
mf: c15h13n3o3s
mw: 315.35
einecs: 258-714-5
product categories: metabolites;veterinaries;amines;aromatics;heterocycles;intermediates & fine chemicals;metabolites & impurities;pharmaceuticals;sulfur & selenium compounds;pharmaceutical intermediate;amines, aromatics, heterocycles, metabolites & impurities, pharmaceuticals, intermediates & fine chemicals, sulfur & selenium compounds;ticlid
mol file: 53716-50-0.mol
oxfendazole structure
oxfendazole chemical properties
melting point 298-300 c
storage temp. 2-8°c
merck 14,6935
cas database reference 53716-50-0(cas database reference)
safety information
risk statements 36
safety statements 26
wgk germany 3
rtecs fd0835000
msds information
provider language
sigmaaldrich english
oxfendazole usage and synthesis
description oxfendazole is a broad spectrum benzimidazole anthelmintic approved for veterinary use. it is effective to protect livestock and poultry from most of the parasites such as roundworms, tapeworms, strongyles and pinworms. the drug is mainly applied in the form of pills, tables, drenches and bolus, etc. especially for horses, goats, cattle, sheep, etc. the drug functions on parasites by binding to tubulin, which is a structural protein of microtubules. in the parasites the blocking of microtubules interferes with the uptake of glucose, which ultimately empties the glycogen reserves. this blocks the whole energy management mechanism of the parasites and eventually leads to death.
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chemical properties of-white solid
uses paf inhibitor
uses a metabolite of fenbendazole (f246750).
definition chebi: a member of the class of benzimidazoles that is fenbendazole in which the sulfur has been oxidised to the corresponding sulfoxide.