TIANFU-CHEM - Tenofovir disoproxil CAS NO.201341-05-1

tenofovir disoproxil basic information

description references

product name: tenofovir disoproxil

synonyms: (r)-(((((1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(oxy))bis(methylene) diisopropyl dicarbonate;(r)-(((((1-(6-amino-9h-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)-bis(oxy))bis(methylene) diis;2,4,6,8-tetraoxa-5-phosphanonanedioicacid, 5-[[(1r)-2-(6-amino-9h-purin-9-yl)-1-methylethoxy]methyl]-,1,9-bis(1-methylethyl) ester, 5-oxide;tenofivirdisoproxilfumarate;sry;testis-determining factor;tenofovir disoproxil, >=98%;tenofovir disoproxil aspartate

cas: 201341-05-1

mf: c19h30n5o10p

mw: 519.44

einecs: 111-111-1

product categories:

mol file: 201341-05-1.mol

tenofovir disoproxil structure

tenofovir disoproxil chemical properties

storage temp. -20°c

safety information

msds information

tenofovir disoproxil usage and synthesis

description tenofovir disoproxil belongs to a class of medications called antiretroviral known as a nucleotide reverse transcriptase inhibitor, which is commonly used to treat the infection caused by the human immunodeficiency virus (hiv) generally in combination with other antiviral agents. it can also be used for prevention of hiv/aids among those people who are at high risk before exposure, such as injection through sexual transmission or injection of drugs. it functions by blocking reverse transcriptase, an enzyme vital to viral duplication in people infected hiv. besides, it is effective to treat chronic hepatitis b, in which it helps prevent the enzymes needed for the hepatitis b virus to reproduce from working properly. however, tenofovir disoproxil does not cure hiv/aids or hepatitis b. it helps lower the amount of hiv or hepatitis b virus in the body and slow down the progression of the disease. tenofovir was patented in 1996 and approved for use in the united states in 2001.

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definition chebi: an organic phosphonate that is the disoproxil ester of tenofovir. a prodrug for tenofovir, an hiv-1 reverse transcriptase inhibitor, tenofovir disoproxil is used as the fumaric acid salt in combination therapy for the treatment of hiv infection.

tenofovir disoproxil preparation products and raw materials