product name: sulfamethazine
synonyms: (p-aminobenzolsulfonyl)-2-amino-4,6-dimethylpyrimidin;2-(4-aminobenzenesulfonamido)-4,6-dimethylpyrimidine;4,6-dimethyl-2-sulfanilamidopyrimidine;4-amino-n-(2,6-dimethyl-2-pyrimidinyl)ben-zenesulfonamide;4-amino-n-(4,6-dimethyl-2-pyrimidinyl)-benzenesulfonamid;4-amino-n-(4,6-dimethyl-2-pyrimidinyl)-benzensulfonamide;4-amino-n-(4,6-dimethyl-2-pyrimiidinyl)benzenesulfonamide;6-(4’-aminobenzol-sulfonamido)-2,4-dimethylpyrimidin
cas: 57-68-1
mf: c12h14n4o2s
mw: 278.33
einecs: 200-346-4
product categories: active pharmaceutical ingredients;antibiotics for research and experimental use;biochemistry;sulfonamides (antibiotics for research and experimental use);intermediates & fine chemicals;pharmaceuticals;sulfur & selenium compounds;pharmaceutical intermediate;sulfasure
mol file: 57-68-1.mol
sulfamethazine chemical properties
mp 197 °c
storage temp. 2-8°c
water solubility 150mg/100ml (29 ºc)
merck 8905
stability: stable, but light sensitive. incompatible with strong oxidizing agents.
cas database reference 57-68-1(cas database reference)
nist chemistry reference sulfamethazine(57-68-1)
epa substance registry system benzenesulfonamide, 4-amino-n-(4,6-dimethyl-2- pyrimidinyl)-(57-68-1)
safety information
hazard codes xi
risk statements 36/37/38
safety statements 23-24/25-36-26
wgk germany 2
rtecs wo9275000
f 10
hazardous substances data 57-68-1(hazardous substances data)
sulfamethazine usage and synthesis
chemical properties white to off-solid
usage antibacterial
general description odorless sticky, white or creamy-white crystalline powder. slightly bitter taste. an antibacterial.
air & water reactions water solubility increases rapidly with increasing ph [merck]. insoluble in water.
reactivity profile sulfamethazine is sensitive to light and may also be sensitive to heat. the presence of oxygen and moisture may accelerate the effects of heat and light .
fire hazard flash point data for sulfamethazine are not available; however, sulfamethazine is probably combustible.
sulfamethazine preparation products and raw materials
raw materials sodium carbonate-->2,4-pentanedione-->cyclohexanone-->sulfaguanidine