Tazarotene CAS NO.118292-40-3

FOB Price:: USD 1.00-1.00 /Kilogram Get Latest Price

Min.Order Quantity:: 1 Kilogram

Purity:: 99%min

Port:: Shanghai,China

Payment Terms:: L/C,D/A,D/P,T/T,

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Product Details

Keywords

118292-40-3
Tazorac
Ethyl 6-((4,4-dimethylthiochroman-6-yl)ethynyl)nicotinate

Quick Details

ProName: Tazarotene
CasNo: 118292-40-3
Molecular Formula: C21H21NO2S
Appearance: crystalline powder
Application: Skin Treatment Drug; Drug Acting on Sk...
DeliveryTime: prompt shipment
PackAge: 25kg drum
Port: Shanghai,China
ProductionCapacity: 2000 Metric Ton/Year
Purity: 99%min
Storage: Stored in dry and cool place, keeping ...
Transportation: by sea,air
LimitNum: 1 Kilogram
Related Substances: 0.25%
Residue on Ignition: 0.5%
Heavy Metal: ≤20ppm
Valid Period: 2 years
CAS No.: 118292-40-3

Superiority

function

tazarotene is an acetylenic retinoid prodrug converted to the active metabolite, tazarotenic acid, with selective affinity for retinoic acid receptors rarβ and rarγ. tazarotene also upregulates tigs (tazarotene-induced genes), including the cell adhesion molecule tig1 and the tumor-suppressor tig3.

application

pharmaceutical raw materials

tazarotene is third class daiwei formic acid skin drugs, topical retinoids of precursor drugs for skin, regulate skin cell differentiation and proliferation, and so on, mainly is suitable for the treatment of plaque type psoriasis.

Details

specification

items		specification	results
bp2010 /ep6	appearance	crystalline powder	conforms
	melting point	about 205°c	206.4°c~206.7°c
	identification	meet the requirements	conforms
	appearance of solution	clear, not more intense than y7	conforms
	ph	2.4~3.0	2.60
	loss on drying	≤0.5%	0.04%
	sulphated ash	≤0.1%	0.01%
	heavy metals	≤20 ppm	<20 ppm
	related substances	≤0.25%	conforms
	assay	99.0%~101.0%	99.8%
usp32	identification	meet the requirements	conforms
	loss on drying	≤0.5%	0.04%
	residue on ignition	≤0.1%	0.01%
	heavy metals	≤0.003%	<0.003%
	residue solvent - ethanol	≤0.5%	<0.04%
	chloride	16.9%~17.6%	17.1%
	assay	98.0%~102.0%	100.0%
conclusion: the product complies with bp2010/usp32/ep6 standard