Tolfenamic Acid CAS NO.13710-19-5

inspect item

specification

results

appearance

white or slightly yellow, crystalline powder

conforms

solubility

practically insoluble in water, soluble in dimethylformamide, sparingly soluble in ethanol and in methylene chloride

conforms

identification

a. light absorption: the ratio of the absorbance measured at the maximum at 286nm to that maximum at 345nm should be 1.2 to 1.4

conforms

b. ir absorption spectrophotometry should be conformed

1.2

c. tlc chromatography (245nm) should be conformed

conforms

melting point

210~214℃

212.1~212.6℃

related substances

impurity a<0.1%;impurity b<0.05%

conforms

any other impurity<0.1%

conforms

total impurity<0.5%

conforms

copper

not more than 10ppm

conforms

loss on drying

not more than 0.5%

0.20%

sulphated ash

not more than 0.1%

<0.1%

assay (basis on dry)

99.0~101.0%

99.70%

conclusion

the results conforms with ep6.0 standards