treat pain and fever powder paracetamol / acetaminophen / apap cas: 103-90-2

product description:

paracetamol, also known as acetaminophen or apap, is a medication used to treat pain and fever.it is typically used for mild to moderate pain relief.evidence for its use to relieve fever in children is mixed.it is often sold in combination with other ingredients such as in many cold medications.in combination with opioid pain medication, paracetamol is also used for more severe pain such as cancer pain and pain after surgery. it is typically used either by mouth or rectally but is also available intravenously.effects last between two and four hours.

paracetamol is generally safe at recommended doses.serious skin rashes may rarely occur, and too high a dose can result in liver failure.it appears to be safe during pregnancy and when breastfeeding.in those with liver disease, it may still be used, but in lower doses.paracetamol is classified as a mild analgesic.it does not have significant anti-inflammatory activity and how it works is not entirely clear.

paracetamol was discovered in 1877.it is the most commonly used medication for pain and fever in both the united states and europe.it is on the world health organization's list of essential medicines, the most effective and safe medicines needed in a health system.paracetamol is available as a generic medication with trade names including tylenol and panadol among others.the wholesale price in the developing world is less than 0.01 usd per dose.in the united states it costs about 0.04 usd per dose.

paracetamol spec.

4-acetamidophenol
cas: 103-90-2
mf: c8h9no2
mw: 151.16
einecs: 203-157-5
chemical properties white solid
usage antiinfectant
usage dispersing agent in liquid scintillation counting
usage analgesic; antipyretic
general description odorless white crystalline solid. bitter taste. ph (saturated aqueous solution) about 6.
air & water reactions slightly soluble in water.
reactivity profile 4-acetamidophenol is sensitive to light. incompatible with strong oxidizers. .
fire hazard flash point data for 4-acetamidophenol are not available; however, 4-acetamidophenol is probably combustible.
biological activity cyclooxygenase inhibitor; may be selective for cox-3 (ic 50 values are 460, > 1000 and > 1000 μ m for canine cox-3, and murine cox-1 and cox-2 respectively). widely used analgesic and antipyretic agent.

paracetamol usage:

1. antipyretic analgesics, international non proprietary drug called paracetamol. it is the most commonly used non anti-inflammatory antipyretic analgesic, antipyretic effect similar to aspirin, the analgesic effect is weak, no anti rheumatic effects of anti inflammation, is the best varieties of acetanilide drugs. particularly suitable for carboxylic acid can not be used drugs patients. for the common cold, toothache embolism. acetaminophen is intermediate in organic synthesis, hydrogen peroxide stabilizer, photographic chemicals.
2. used as antipyretic, analgesic, anti rheumatic drugs.