USD $1.80-2.50 / Kilogram
USD $100.00-150.00 / Kilogram
USD $0.40-1.00 / Metric Ton
USD $100.00-150.00 / Kilogram
USD $32.00-34.00 / Metric Ton
api (原料药)
product name: trimethoprim (tmp) 甲氧苄啶 powder or micronized
cas: 738-70-5
specification: bp ep usp
documents: cos, gmp. edmf, fda, cofepris, who, tga
packing: 25kg/drum
product |
trimethoprim micron |
pharmacopoleia |
bp2017 |
batch no. |
201703320 |
gross weight |
29.5kg/drum |
batch quantity |
500kg |
net weight |
25kg/drum |
manufacture date |
mar.10,2017 |
expiry date |
feb,2022 |
analysis date |
mar.10,2017 |
release date |
mar.11,2017 |
test item [characters] appearance solubility
particle size [identification] a:melting point b:specific absorbance c:ir-spectrum d:chemical reaction appearance of solution
[related substances] hplc method a: impurity f any impurity single total impurities hplc method b: any impurity single total impurities heavy metals residul methanol residul dmso residul acetic acid gc impurity k(aniline) loss on drying sulphated ash assay |
standards required
white or yellowish-white powder very slightly soluble in water, slightly soluble in alcohol. 90% pass 45micron
199—203℃ max.287nm:240-250 complies with reference spectrum green fluorescence at 365nm not more intensely colored than reference solution by7
≤0.1% ≤0.1% ≤0.2%
≤0.1% ≤0.2% ≤20ppm ≤3000ppm ≤5000ppm ≤5000ppm ≤5ppm ≤1.0 ≤0.1% 98.5—101.0% |
test results
white-yellowish-white powder very slightly soluble in water, slightly soluble in alcohol 90% pass 45micron
201.5—202.0℃ 246 complies with reference spectrum green fluorescence at 365nm not more intensely colored than reference solution by7
0.073% <0.1% <0.2%
<0.1% <0.2% <20ppm below detection limited below detection limited below detection limited below detection limited 0.2% 0.05% 99.8% |
|
results:the commodity meets the standard of bp2017 |
product |
trimethoprim micron |
pharmacopoleia |
bp2017 |
batch no. |
201603320 |
gross weight |
29.5kg/drum |
batch quantity |
500kg |
net weight |
25kg/drum |
manufacture date |
mar.10,2017 |
expiry date |
feb,2022 |
analysis date |
mar.10,2017 |
release date |
mar.11,2017 |
test item [characters] appearance solubility
particle size [identification] a:melting point b:specific absorbance c:ir-spectrum d:chemical reaction appearance of solution
[related substances] hplc method a: impurity f any impurity single total impurities hplc method b: any impurity single total impurities heavy metals residul methanol residul dmso residul acetic acid gc impurity k(aniline) loss on drying sulphated ash assay |
standards required
white or yellowish-white powder very slightly soluble in water, slightly soluble in alcohol. 90% pass 45micron
199—203℃ max.287nm:240-250 complies with reference spectrum green fluorescence at 365nm not more intensely colored than reference solution by7
≤0.1% ≤0.1% ≤0.2%
≤0.1% ≤0.2% ≤20ppm ≤3000ppm ≤5000ppm ≤5000ppm ≤5ppm ≤1.0 ≤0.1% 98.5—101.0% |
test results
white-yellowish-white powder very slightly soluble in water, slightly soluble in alcohol 90% pass 45micron
201.5—202.0℃ 246 complies with reference spectrum green fluorescence at 365nm not more intensely colored than reference solution by7
0.073% <0.1% <0.2%
<0.1% <0.2% <20ppm below detection limited below detection limited below detection limited below detection limited 0.2% 0.05% 99.8% |
|
results:the commodity meets the standard of bp2017 |