Welcome to LookChem.com Sign In|Join Free
  • or
HENAN SUNLAKE ENTERPRISE CORPORATIONVitamin D2//file1.lookchem.com/cas/reactions/2021/05/28/1916682.png
qq

Communicate with Supplier:

Ms. summer
Ms. summer: What can I do for you?

Vitamin D2 CAS NO.50-14-6

Min.Order Quantity:
1 Gram
Purity:
98% Min
Port:
Shanghai Port
Payment Terms:
L/C,D/A,D/P,T/T,MoneyGram,Other

Add to Inquiry Cart

Product Details

Keywords

  • VIOSTEROL
  • 50-14-6 supplier
  • 50-14-6 price

Quick Details

  • ProName: Vitamin D2
  • CasNo: 50-14-6
  • Molecular Formula: C28H44O
  • Appearance: white needle crystal or crystalline po...
  • Application: FOR RESEARCH USE ONLY
  • DeliveryTime: Within 7 working days
  • PackAge: 1g,5g,10g...1kg,5kg...more
  • Port: Shanghai Port
  • ProductionCapacity: 100 Kilogram/Month
  • Purity: 98% Min
  • Storage: Protected from light, stored hermetica...
  • Transportation: By air or sea
  • LimitNum: 1 Gram
  • Molecular Weight: 396.65

Superiority

henan sunlake enterprise corporation

our company advantages:

1、the highest quality with the competitive price.

2、professional human services.

3、the fastest and safest delivery service.

4、the faster and safest delivery service.

5、the high purity products.

6、we have a sufficient supply of stock.

7、a variety of payments, such as l/c, tt, , moneygram or other payments.

Details

vitamin d2 basic information
vitamin d toxicity limited use the maximum allowable amount as food additives and maximal allowable residue limits chemical properties uses production method
product name: vitamin d2
synonyms: vitamin d;vitamin d2;vitamin d2 water;viosterol;(3beta,5z,7e,22e)-9,10-secoerga-5,7,10(19),22-tetraen-3-ol;(3beta,5z,7e,22e)-9,10-secoergosta-5,7,10(19)-,22-tetraen-3-ol;(3-beta,5z,7e,22e)-9,10-secoergosta-5,7,10,(19),22-tetraen-3-ol;(5e,7e,22e)-9,10-secoergosta-5,7,10,22-tetraen-3-ol
cas: 50-14-6
mf: c28h44o
mw: 396.65
einecs: 200-014-9
product categories: vitamins - deuterated;biochemistry;vitamins;nutritional supplements;vitamins and derivatives;chiral reagents;intermediates & fine chemicals;pharmaceuticals;mainly used for the prevention and treatment of rickets osteomalacia baby brothers tetany, etc;vitamin series;drisdol;isolabel;inhibitors
mol file: 50-14-6.mol
vitamin d2 structure
vitamin d2 chemical properties
mp 114-118 °c(lit.)
alpha 82 º (c=3, in acetone 25 ºc)
fp 14 °c
storage temp. 2-8°c
solubility h2o: 200 mg/ml, clear to hazy
form powder
merck 10018
cas database reference 50-14-6(cas database reference)
nist chemistry reference ergocalciferol(50-14-6)
epa substance registry system 9,10-secoergosta- 5,7,10(19),22-tetraen-3-ol, (3.beta.,5z,7e,22e)-(50-14-6)
safety information
hazard codes xn,t+,t,f
risk statements 22-48/25-26-24/25-40-23/24/25-48/22-23-11-20
safety statements 28-36/37-45-28a-36-26-36/37/39-22-16-7
ridadr un 2811 6.1/pg 2
wgk germany 3
rtecs ke1050000
f 1-8-10
hazardclass 6.1(a)
packinggroup ii
hazardous substances data 50-14-6(hazardous substances data)
msds information
provider language
vitamin d2 english
sigmaaldrich english
acros english
vitamin d2 usage and synthesis
vitamin d vitamin d refers to a group of fat-soluble steroid compounds with anti-rickets effect and is called anti-rickets vitamin. it is known currently about at least ten or more sterols substance with vitamin d activity. they are mainly presented in the vegetable oil or yeast ergosterol solid which subject to sunlight or ultraviolet irradiation to generate vitamin d2 which is also called as calciferol or ergocalciferol. therefore, ergosterol is also called as original vitamin d2; the other is from that the human body can convert the cholesterol to the 7- dihydro-cholesterol to be stored in the skin with the later being able to be converted to vitamin d3 upon sunlight and ultraviolet radiation. vitamin d3 is also known as cholecalciferol and therefore the 7-dehydrocholesterol is also known as original vitamin d3. vitamin d2 has a very similar structure with vitamin d3 and both of them are the b ring open-ring derivatives of precursor sterols with the difference of them being laid in a extra double bond and a methyl group in the side chain of vitamin d2.
both vitamin d2 and vitamin d3 are colorless or white crystals and are not foul with the melting point being 115 ~ 118 ℃ and 84 ~ 85 ℃, respectively. they are insoluble in water and easily soluble in alcohol, ether, acetone, and slightly soluble in vegetable oil. they are unstable in air and sunlight and are easily inactivated in moist air. however, vitamin d3 is relatively more stable than vitamin d2. these two have similar physiological roles in the human body with the major role being maintain the normal metabolism of calcium and phosphorus, promoting the deposition of calcium and phosphorus into the bone and tissue and thus it can be used in prevention and treatment of metabolic bone disease such as rickets and osteomalacia.
vitamin d2 and d3 have the same effects on mammals and cows and pigs. however, vitamin d3 has a ten times stronger activity on poultry (birds) than vitamin d2.
vitamin d deficiency can reduce the intestinal absorption of calcium and cause the decomposition of bone calcium and phosphorus. young livestock will get osteomalacia and adult animals are prone to osteoporosis. vitamin d deficiency can also lead to animal sternum and spine deformation and that layers give birth to soft-shell eggs. because vitamin d control the absorption of calcium, phosphorus, too much absorption of vitamin d in the diet can cause high blood calcium, so that excess calcium can be deposited in the heart, blood vessels, joints, pericardium or intestinal wall, leading to heart failure, joint stiffness or intestines disorders.
sunbathing is the most economical source of getting vitamin d. the ergosterol or 7-dehydrocholesterol can be converted into vitamin d inside animal body upon ultraviolet radiation. the hay, yeast, corn leaves, barley, oats, wheat under sunshine and yeast which has been subject to ultraviolet treatment is a good source of vitamin d. animal products can directly provide vitamin d for the livestock, such as eggs, milk. cod liver oil is rich in vitamin d levels. reared animals and animal with insufficient sunlight need to have their daily feed supplied with additional vitamin d.
the above information is edited by the chemicalbook of dai xiongfeng.
toxicity acute toxicity dose: 100 mg/d (adult, orally). mouse lethal dose of 20mg / kg (6 day). excess can easily cause poisoning.
gras (fda, §182.5950, 2000).
ld50: 42mg/kg (rat, oral).
limited use gb 14880-94 (μg / kg): liquid milk from 10 to 20; margarine: 125 to 156; dairy products: 63 to 125; milk and milk drinks: 10 to 40; infant and children food: 50 to 115.
gb 2760-2002 (pg / kg): solid drink, ice cream, 10 to 20; arrowroot flour: 50 to 100; soy milk, soy flour, 15 to 60; soy milk, soy milk, 3 to 15; jelly: 10 to 40; instant breakfast cereals, 12.5 to 37.5; puffed food sandwich from 10 to 60.
fda, §184.1950 (iu / 100g; 2001): breakfast cereals 350; 90 granular and pasty products; milk 42; 89 dairy products.
the maximum allowable amount as food additives and maximal allowable residue limits the maximum allowable amount as food additives and maximal allowable residue limits
chemical properties it is white needle crystal or crystalline powder and is odorless and tasteless. its melting point is 115-118 ℃ (decomposition), its specific rotation is [α]20d+102.5°(ethanol). the ethanol solution of this product has maximum absorption at 265nm wavelength. it is soluble in ethanol (1: 2), diethyl ether (1: 2), acetone (1:10) and chloroform (1: 0.7) but insoluble in water. moreover, it has a lower activity in case of light or oxygen.
uses it can be applied to biochemical studies; its clinical drug belongs to a lipid-soluble vitamin which can promote the intestinal absorption of calcium and phosphorus which plays a role of facilitating the calcification of bone. it is clinically used for prevention and treatment of rickets in children and adult osteomalacia.
vitamin d2 can maintain the normal metabolism of calcium and phosphorus and can also promote the body's absorption of calcium and phosphorus. upon its deficiency, the children are easy to get rickets. china ruled that it can be applied for strengthening margarine with the usage amount being 125 ~ 156 μg / kg; its usage amount in fortified dairy is 63 ~ 125μg / kg; the usage amount in strengthening infant and children food used is 50 ~ 100μg / kg; the usage amount in strengthening milk or milk beverage is 10 ~ 40μg / kg; the maximal allowable usage amount in the strengthening solid drinks and ice cream is 10 ~ 20μg / kg.
it is mainly applied to the prevention and treatment of rickets, osteomalacia, and infant tetany psychosis.
production method dissolve the ergosterol dissolved in ethanol and go through ring-opening under uv illumination; the reaction was further concentrated under reduced pressure, frozen, filtered, and filtered of liquid nitrogen, and concentrated under reduced pressure to dryness to obtain the crude oil of vitamin d2 with distillation to obtain the refined products.
vitamin d2 is naturally presented in the liver, egg yolk and milk; the production method of the industry starts with extracting the ergocalciferol from vegetable oil or yeast extract in the body. further dissolve it in chloroform or cyclohexane, and then convert it to the vitamin d2 through ultraviolet radiation on the quartz glass flask.
ergosterol ethanol solution is subject to ultraviolet radiation with the 9’, 10’ bond breakage to obtain the vitamin d2 crude product; the later one further has esterification with 3, 5-nitrobenzoyl chloride and undergoes alkaline hydrolysis to get the purified product.
chemical properties crystalline
usage the synthetic form of vitamin d. prepared from ergosterol by uv irradiation in a suitable solvent. commercial solutions are usually made with propylene glycol or sesame oil. antirachitic
usage antirachitic vitamin; ld50 (rat) 56 mg/kg po
general description odorless white crystals. used as a dietary supplement and food additive.
reactivity profile flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. they react with oxoacids and carboxylic acids to form esters plus water. oxidizing agents convert them to aldehydes or ketones. alcohols exhibit both weak acid and weak base behavior. they may initiate the polymerization of isocyanates and epoxides.
health hazard vitamin d2 poisoning disturbs calcium metabolism and causes kidney damage. vitamin d2 in a single acute ingestion presents no toxic hazards. daily ingestion in excess of 5000 units/day in children or 7500 units/day in adults will produce toxic symptoms associated with hypervitaminosis d. those with hypercalcemia are at a greater risk.
fire hazard shows signs of decomposition when stored for a few days at room temperature.
vitamin d2 preparation products and raw materials
raw materials chloroform-->azabenzene-->cyclohexane-->passion flower oil-->silica glass-->3,5-dinitrobenzoyl chloride-->ergosterol

company information

henan sunlake enterprise corporation is located in henan province , the central plain of china , which enjoys favorable geogeaphical position and convenient transportion. the com[any was established in june. 1998, until now having more than 18 years experience in manufacturing & exporting chemical raw material .

sunlake is a professional manufacturer engaged in producing and selling chemicals,including organic & inorganic chemicals , pigments & dyestuffs , water treatment chemicals , food & feed additives and others. these products have been being well exported to europe, southeast asia, the middle east ,africa, south america and some other countries and areas.

we sincerely welcome foreign friends to visit our plant for cooperation. with the idea of "quality first,credit priority, excellent service", we are highly acknowledged by customers for good quality and competitive price. more importantly , the company has a strong r & d team, who are professional engineers and scholars with ph. d. .so we are confident to serve you better with our high - quality products and professional team. we are taking great efforts to provide our customers with demanded goods and professional services, and continuously improve our core ability of competition and get the momentum for sustainable development, and finally make us being a reliable and professional supplier in international market.

we welcome any serious inquiries from all customers of the world, and sincerely hope to cooperate with you for a brilliant future!

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)