buying Epothilone B 152044-54-7 exporter CAS NO.152044-54-7

Min.Order Quantity:: 0 Metric Ton

Purity:: 99%min

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Epothilone B 152044-54-7
buying Epothilone B
Epothilone B exporter

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ProName: buying Epothilone B 152044-54-7 expor...
CasNo: 152044-54-7
Molecular Formula: C27H41NO6S
Appearance: White crystalline powder
Application: API
DeliveryTime: In stock
PackAge: aluminous bag
ProductionCapacity: 10 Kilogram/Year
Purity: 99%min
Storage: hading, sealed, dry place.
Transportation: hading, sealed, dry place.
LimitNum: 0 Metric Ton

Superiority

1.advanced production line and professional r&d team

2.our products are all with good quality and best price

3.strong supply capacity

4.fast & safe shipment and delivery on time

5.we can offer customized product

product name		epothilone b	cas:	152044-54-7
batch no.		2013.04.10	report date	2013.04.12
quantity		10g	retest period:	2015.05.01
contents of testing		specifications		results
characters	appearance	white crystalline		white crystalline
	solubility	easily soluble in methanol		conform
	specific optical rotation	-35°~-38°(c=0.7%,in methanol)		-36.4°
identification	a: absorption maximum	uv max(in methanol):211nm, 249nm		conform
	b:ir	ir spectrum of the sample corresponds to that of the reference standard		conform
	c:hplc	the reference time of the major peak in the chromatograms corresponds to that in the reference standard.		conform
test	related compounds	epothilone a: not more than 1.5%		0.32%
		maximum individual impurity: not more than 1.0%		0.26%
		total impurities:not more than 2.0%		0.82%
	residual organic solvent	methanol: not more than 3000ppm		1263ppm
		ethyl acetate: not more than 5000ppm		809ppm
	water	not more than 5.0%		2.6%
	reside on ignition	not more than 0.2%		0.1%
purity(hplc)		not less than 98.0%		99.2%
conclusion: all items comply with the inner quality standard.

Details

1.advanced production line and professional r&d team

2.our products are all with good quality and best price

3.strong supply capacity

4.fast & safe shipment and delivery on time

5.we can offer customized product

product name		epothilone b	cas:	152044-54-7
batch no.		2013.04.10	report date	2013.04.12
quantity		10g	retest period:	2015.05.01
contents of testing		specifications		results
characters	appearance	white crystalline		white crystalline
	solubility	easily soluble in methanol		conform
	specific optical rotation	-35°~-38°(c=0.7%,in methanol)		-36.4°
identification	a: absorption maximum	uv max(in methanol):211nm, 249nm		conform
	b:ir	ir spectrum of the sample corresponds to that of the reference standard		conform
	c:hplc	the reference time of the major peak in the chromatograms corresponds to that in the reference standard.		conform
test	related compounds	epothilone a: not more than 1.5%		0.32%
		maximum individual impurity: not more than 1.0%		0.26%
		total impurities:not more than 2.0%		0.82%
	residual organic solvent	methanol: not more than 3000ppm		1263ppm
		ethyl acetate: not more than 5000ppm		809ppm
	water	not more than 5.0%		2.6%
	reside on ignition	not more than 0.2%		0.1%
purity(hplc)		not less than 98.0%		99.2%
conclusion: all items comply with the inner quality standard.

a compound isolated from the myxobacterium sorangium cellulosum. similar to paclitaxel,epothilone b induces microtubule polymerization andstabilizes mirotubules against depolymerization conditions. in addition to promoting tubulin polymerization and stabilization of microtubules, this agent is cytotoxic for cells overexpressing p-glycoprotein, a characteristic that distinguishes it from the taxanes. epothilone b may cause complete cell-cycle arrest.

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