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Triumph International Development Limiltedcabozantinib (S)-malate//file1.lookchem.com/300w/substances/2022-02-14-06/c0bc4631-bfbc-4e29-b310-a025eb81f7c2.png
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cabozantinib (S)-malate CAS NO.1140909-48-3

Min.Order Quantity:
100 Metric Ton
Purity:
98%min
Port:
Qingdao,China
Payment Terms:
L/C,T/T,MoneyGram,Other

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Product Details

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  • 1140909-48-3
  • Sell high quality cabozantinib (S)-malate produced in China factory
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Quick Details

  • ProName: cabozantinib (S)-malate
  • CasNo: 1140909-48-3
  • Molecular Formula: C28H24FN3O5.C4H6O5
  • Appearance: white powder
  • Application: Used for research and industrial manuf...
  • DeliveryTime: Within7-10 days after receipt of your ...
  • PackAge: As customer request
  • Port: Qingdao,China
  • ProductionCapacity: 100kg/Month Metric Ton/Day
  • Purity: 98%min
  • Storage: Store in a cool,dry place and keep awa...
  • Transportation: Common products:Sea/Air/Courier Dange...
  • LimitNum: 100 Metric Ton

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lorcaserin(856681-05-5)is an orally administered agent and a selective 5-ht2c receptor agonist for the treatment of obesity. it had been approved for marketing in us by fda on 27 june in 2012. in clinical studies, lorcaserin has demonstrated efficacy in obese and overweight populations by promoting weight loss and improving metabolic parameters, and it is well tolerated.

Details

quick details

  • proname: cabozantinib malate
  • casno: 1140909-48-3
  • molecular formula: c32h30fn3o10
  • appearance: powder
  • application: 1140909-48-3
  • deliverytime: within 3-7 days
  • package: as requested
  • port: china main port
  • productioncapacity: 300 kilogram/month
  • purity: 98%
  • storage: store in cool, dry place
  • transportation: by sea or by air
  • limitnum: 1 kilogram

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cabozantinib malate basic information
product name: cabozantinib malate
synonyms: (2s)-2-hydroxybutanedioic acid compd. with n-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (1:1);cabozantinib (s)-malate;cabozantinib l-malate salt;n-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]phenyl]-n'-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide (2s)-;cabozantinib (s)-malate(xl-184);cabozantinib l-malate;cabozantinib malate (xl184);xl-184 (malate)
cas: 1140909-48-3
mf: c32h30fn3o10
mw: 635.5931032
einecs:
product categories: inhibitors
mol file: 1140909-48-3.mol
cabozantinib malate structure
cabozantinib malate chemical properties
safety information
msds information
cabozantinib malate usage and synthesis
chemical properties off-white solid
usage cabozantinib is a small molecule c-met modulator. cabozantinib acts as a potent multitargeted vegfr2, met, flt3, tie2, kit and ret inhibitor with ic50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nm for vegfr2, met, flt3, tie2 and kit, respectively. cabozantinib shows dose-dependent inhibition of tumor growth and tumor regression, associated with disruption of the tumor vasculature and extensive tumor cell a poptosis.
usage xl184 (cabozantinib, bms-907351) is a potent multitargeted vegfr2, met, flt3, tie2, kit and ret inhibitor with ic50 of 0.035, 1.8, 14.4, 14.3 and 4.6 nm for vegfr2, met, flt3, tie2 and kit, respectively.
usage cabozantinib malate is the malate of cabozantinib, a potent vegfr2 inhibitor with ic50 of 0.035 nm and also inhibits c-met, ret, kit, flt-1/3/4, tie2, and axl with ic50 of 1.3 nm, 4 nm, 4.6 nm, 12 nm/11.3 nm/6 nm, 14.3 nm and 7 nm, respective

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