tianfu chem Scopolamine hydrobromide CAS NO.114-49-8

scopolamine hydrobromide basic information
product name: scopolamine hydrobromide
synonyms: benzeneacetic acid, a-(hydroxymethyl)-, (1a,2b,4b,5a,7b)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-ylester, hydrobromide (1:1), (as)-;scopolamine-d3 hbr 3h2o;hyosol;tranaxine;scopolamine hbr trihydrate;scopolaminehydrobromidetrihydra;(αs)-α-(hydroxymethyl)-benzeneacetic acid-(1α,2β,4β,5α,7β)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester;( )-scopolamine hydrobromide hydrate
cas: 114-49-8
mf: c17h22brno4
mw: 384.26
einecs: 204-050-6
product categories: api;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from chinese medicinal herbs (tcm).;standardized herbal extract;inhibitors;alkaloids;aromatics;heterocycles;intermediates & fine chemicals;pharmaceuticals;isotope labeled compounds;acetylcholine receptor
mol file: 114-49-8.mol
scopolamine hydrobromide structure
scopolamine hydrobromide chemical properties
melting point 195-199 °c (dry matter)(lit.)
alpha d25 -24 to -26° (c = 5, calculated on anhydrous basis)
storage temp. store at rt
solubility h2o: 50 mg/ml
form powder
color white to off-white
cas database reference 114-49-8(cas database reference)
epa substance registry system benzeneacetic acid, .alpha.-(hydroxymethyl)-, (1.alpha.,2.beta.,4.beta., 5.alpha.,7.beta.)-9-methyl- 3-oxa-9-azatricyclo[3.3.1. 02,4]non-7-yl ester, hydrobromide, (.alpha.s)-(114-49-8)
safety information
hazard codes xn
risk statements 22
safety statements 36
ridadr un 1544 6.1/pg 1
wgk germany 3
rtecs ym4550000
f 3-8

scopolamine hydrobromide usage and synthesis
chemical properties off-white solid
uses an acetylcholine antagonist. used in treatment of motion sickness; antiemetic; antispasmodic; mydriatic; preanesthetic medicant
definition chebi: a hydrobromide that is obtained by reaction of scopolamine with hydrogen bromide.
general description colorless crystals or white powder or solid. has no odor. ph (of 5% solution): 4-5.5. slightly efflorescent in dry air. bitter, acrid taste.
air & water reactions sensitive to air, light and moisture. water soluble.
reactivity profile scopolamine hydrobromide is incompatible with acids, bases and oxidizing agents. .
fire hazard flash point data for scopolamine hydrobromide are not available; however, scopolamine hydrobromide is probably combustible.
biological activity non-selective muscarinic antagonist. widely used clinically to treat motion sickness.