top Betamethasone 21-phosphate disodium CAS NO.151-73-5

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Min.Order Quantity:: 1 Gram

Purity:: 99%

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Betamethasone 21-phosphate disodium
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Quick Details

ProName: top Betamethasone 21-phosphate disodiu...
CasNo: 151-73-5
Molecular Formula: C22H28FNa2O8P
Appearance: Colorless to light yellow liquid
Application: Used in a base-free iridium-catalyzed ...
DeliveryTime: With about 7-10 days after receipt the...
PackAge: as you requested
Port: China main port
ProductionCapacity: 10 Kilogram/Day
Purity: 99%
Storage: room temperature
Transportation: by courier
LimitNum: 1 Gram
Transportation: by courier

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1.noble metal catalysts (pt.pd...)

2.organic phosphine ligands (tert-butyl-phosphine.cyclohexyl-phosphine...)

3.oled intermediates (fluorene,carbazole,boric acid...)

4.customs synthesis

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Details

product name:	betamethasone 21-phosphate disodium
synonyms:	20-dione,9-fluoro-11-beta,17,21-trihydroxy-16-beta-methyl-pregna-4-diene-3;21-(dihydrogenphosphate),disodiumsalt;bentelan;betamethasone sodium phosphate (500 mg)k0c3580.993mg/mg(an);betamethasone sodium phosphate (500 mg);betamethasone 21-pho;(11β,16β)-9-fluoro-11,17-dihydroxy-16-methyl-21-(phosphonooxy)pregna-1,4-diene-3,20-dione sodium salt;9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene -3,20-dione 21-(dihydrogen phosphate) sodium salt
cas:	151-73-5
mf:	c22h28fna2o8p
mw:	516.4
einecs:	205-797-0
product categories:	intermediates & fine chemicals;pharmaceuticals;phosphorylating and phosphitylating agents;steroids;celestone;betamethasone;hormones;steroid hormones
mol file:	151-73-5.mol

betamethasone 21-phosphate disodium chemical properties

merck	14,1180
epa substance registry system	pregna-1,4-diene- 3,20-dione, 9-fluoro-11,17-dihydroxy-16- methyl-21-(phosphonooxy)-, disodium salt, (11.beta.,16.beta.)-(151-73-5)

safety information

hazard codes	xn
risk statements	22
safety statements	36
wgk germany	3
rtecs	tu4056500

msds information

provider	language
sigmaaldrich	english

betamethasone 21-phosphate disodium usage and synthesis

indications and usage	betamethasone sodium phosphate, also called bentelan, betnesol, betamethasone phosphate, and celestone phosphate, is an adrenal cortex hormone, an isomer of dexamethasone with the same effects as prednisolone and dexamethasone. it is mainly used against inflammation and allergies. its effects are the same as those of dexamethasone, and its anti-inflammatory effects are stronger than dexamethasone, prednisone, and cortisone, with fewer side effects. it is used to treat active rheumatism, rheumatoid arthritis, lupus erythematosus, severe bronchial asthma, severe dermatitis, acute leukemia, allergic dermatitis, eczema, neurodermatitis, seborrheic dermatitis, pruritis, and comprehensively treat some infections.
mechanisms of action	betamethasone sodium phosphate has pharmacological effects in treating inflammation, rheumatism, allergies, and immunosuppressive conditions. its anti-inflammatory effects are stronger than those of dexamethasone, triamcinolone, and hydrocortisone. it can reduce and prevent tissue response to inflammation, partly eliminating non-infectious inflammation caused by fever, redness, and swelling, thereby reducing the presence of swelling. the anti-inflammatory effects of 0.3 mg of betamethasone sodium phosphate are comparable to those of 0.75 mg of dexamethasone, 5 mg of prednisone, or 25 mg of cortisone. its sodium retention effects are more than a hundred times those of cortisone. in case of primary adrenal hypofunction, together with corticosteroids, it can be used to replace treatment or prevention, or inhibit of cellular immune response, delay allergic reaction, and reduce the extension of the primary immune response, suitable for low renin and low aldosterone syndrome and orthodontic hypotension caused by autonomic neuropathy.
contraindications	not for use by those with a history of serious mental illness, active duodenum, gastric ulcers, recent gastrointestinal anastomosis, serious osteoporosis, pronounced diabetes, or serious high blood pressure, viruses which cannot be treated by antibiotics, bacterial of fungal infection, thrombophlebitis, or infectious skin diseases such as impetigo, tinea corporis, or tinea cruris.
category	toxic
toxicity level	medium
acute toxicity	oral administration - mice ld50: >4500 mg/kg
flammability	flammable; produces toxic fluoride fumes
storage and transport	store in a cool, ventilated, and dry place
extinguishing agents	dry powder, foam, sand, carbon dioxide, mist
uses	a betamethasone
uses	antiinflammatory, glucocorticoid
uses	nasal, ophthalmic, oral, parenteral
uses	an anti-inflammatory agent
definition	chebi: an organic sodium salt that is the disodium salt of betamethasone phosphate.