1.Identification
1.1 GHS Product identifier
| Product name | boric acid |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | Borsaure |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | For industry use only. Enzymes and Enzyme Stabilizers |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
1.5 Emergency phone number
| Emergency phone number | - |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
2.Hazard identification
2.1 Classification of the substance or mixture
Reproductive toxicity, Category 1B
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |  |
|---|---|
| Signal word | Danger |
| Hazard statement(s) | H360FD |
| Precautionary statement(s) | |
| Prevention | P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P280 Wear protective gloves/protective clothing/eye protection/face protection. |
| Response | P308+P313 IF exposed or concerned: Get medical advice/ attention. |
| Storage | P405 Store locked up. |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| boric acid | boric acid | 10043-35-3 | none | 100% |
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest.
In case of skin contact
Rinse and then wash skin with water and soap.
In case of eye contact
Rinse with plenty of water (remove contact lenses if easily possible).
If swallowed
Rinse mouth. Do NOT induce vomiting. Refer immediately for medical attention.
4.2 Most important symptoms/effects, acute and delayed
Although no adverse effects have been reported from inhaling boric acid dust, it is absorbed through mucous membranes. Ingestion of 5 grams or more may irritate gastrointestinal tract and affect central nervous system. Contact with dust or aqueous solutions may irritate eyes; no chronic effects have been recognized, but continued contact should be avoided. Dust and solutions are absorbed through burns and open wounds but not through unbroken skin. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
The diagnoses of boric acid poisoning can be confirmed with the measurement of blood or serum boric acid levels (nL=1.4 nmol/mL), but this test is not routinely available. Treatment of boric acid toxicity is mainly supportive. Activated charcoal is not recommended because of its relatively poor adsorptive capacity for boric acid. In cases of massive oral overdose or renal failure, hemodialysis, or perhaps exchange transfusion in infants, may be helpful in shortening the half-life of boric acid.
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
Fire Extinguishing Agents: Water fog. (USCG, 1999)
5.2 Specific hazards arising from the chemical
Literature sources indicate that this compound is nonflammable.
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.
6.3 Methods and materials for containment and cleaning up
Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Separated from strong bases.Preserve in well-closed containers.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
no data available
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
| Physical state | colourless or white odourless crystalline solid |
|---|---|
| Colour | Colorless, transparent crystals or white granules or powder |
| Odour | Odorless |
| Melting point/ freezing point | 169oC |
| Boiling point or initial boiling point and boiling range | 300oC |
| Flammability | Not combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| Lower and upper explosion limit / flammability limit | no data available |
| Flash point | no data available |
| Auto-ignition temperature | no data available |
| Decomposition temperature | 171°C |
| pH | 3,8-4,8 (3,3?% aqueous solution) |
| Kinematic viscosity | no data available |
| Solubility | In water:49.5 g/L (20 oC) |
| Partition coefficient n-octanol/water (log value) | log Kow = 0.175 |
| Vapour pressure | 2.6 mm Hg ( 20 °C) |
| Density and/or relative density | 1.437g/cm3 |
| Relative vapour density | no data available |
| Particle characteristics | no data available |
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
Stable in air.
10.3 Possibility of hazardous reactions
Not flammableBORIC ACID is a very weak acid. Incompatible with alkali carbonates and hydroxides. During an attempt to make triacetyl borate, a mixture of boric acid and acetic anhydride exploded when heated to 58-60°C [Chem. Eng. News 51:(34) 1973]. Reacts violently with the strong reducing agent potassium metal.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
During an attempt to make triacetyl borate, a mixture of boric acid and acetic anhydride exploded when heated to 58-60°C.
10.6 Hazardous decomposition products
Boric acid decomposes in heat above 100°C forming boric anhydride and water.
11.Toxicological information
Acute toxicity
- Oral: LD50 Rat oral 3000-4000 mg/kg bw
- Inhalation: LC50 Rat inhalation >0.16 mg/L 4hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
Cancer Classification: Group E Evidence of Non-carcinogenicity for Humans
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
- Toxicity to fish: LC50; Species: Oncorhynchus mykiss (Rainbow trout); Concentration: 100 ppm for 96 hr (soft water); exposure was initiated subsequent to fertilization and maintained through 4 days posthatching /Conditions of bioassay not specified in source examined
- Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water flea); Conditions: static bioassay; Concentration: 133 (115-153) mg/L for 48 hr
- Toxicity to algae: no data available
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
No biotransformation processes have been reported for boron compounds(1). Boric acid has been shown to be a mild antiseptic agent with bacteriostatic action(2). A concentration beyond 10 mg/L produces toxicity to activated sludge cultures(3).
12.3 Bioaccumulative potential
Highly water soluble materials are unlikely to bioaccumulate to any significant degree, and borate species are all present essentially as undissociated boric acid at neutral pH(1). The octanol/water partition coefficient for boric acid has been measured as 0.175(1), indicating low bioaccumulation potential(1). Boron did not bioaccumulate in 47-day and 21-day exposure tests using oysters and sockeye salmon respectively(1).
12.4 Mobility in soil
Boric acid adsorption to illite (three-layered clay consisting of two outer layers of hydrated SiO2 and a central layer of hydrated Al2O3) and kaolinite (alternate layers of SiO2 and Al2O3) clays, as well as activated sludge was studied. The compound was added to 100 mL flasks corresponding to a boron concentration range of zero to 256 mg/L. It was observed that kaollinite adsorbed about 40 times (Kd = 0.199 (Freundlich adsorption coefficient)) more boric acid than illinite (Kd = 0.005) at pH 7; five times as much boric acid adsorbed to activated sludge (Kd = 0.025) as to illinite at pH 7(1). Boron adsorption is influenced by the distribution of boron species (H3BO3; B(OH)4(-)) as well as pH, the type and/or composition of the solution matrix, and surface properties(2). The pKa of boric acid is 9.24(3), indicating that this compound will exist primarily in the undissociated form in the environment, but partially in the anion form in alkaline soils(SRC). However, boric acid is a Lewis acid and therefore behaves as an electron acceptor, rather than a proton donor(3).
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
14.Transport information
14.1 UN Number
| ADR/RID: Not dangerous goods. | IMDG: Not dangerous goods. | IATA: Not dangerous goods. |
14.2 UN Proper Shipping Name
| ADR/RID: unknown |
| IMDG: unknown |
| IATA: unknown |
14.3 Transport hazard class(es)
| ADR/RID: Not dangerous goods. | IMDG: Not dangerous goods. | IATA: Not dangerous goods. |
14.4 Packing group, if applicable
| ADR/RID: Not dangerous goods. | IMDG: Not dangerous goods. | IATA: Not dangerous goods. |
14.5 Environmental hazards
| ADR/RID: no | IMDG: no | IATA: no |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| boric acid | boric acid | 10043-35-3 | none |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
16.Other information
Information on revision
| Creation Date | Aug 12, 2017 |
|---|---|
| Revision Date | Aug 12, 2017 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
