1.Identification
1.1 GHS Product identifier
| Product name | 1,3-dichlorobenzene |
|---|
1.2 Other means of identification
| Product number | - |
|---|---|
| Other names | iazine |
1.3 Recommended use of the chemical and restrictions on use
| Identified uses | For industry use only. Volatile organic compounds |
|---|---|
| Uses advised against | no data available |
1.4 Supplier's details
1.5 Emergency phone number
| Emergency phone number | - |
|---|---|
| Service hours | Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours). |
2.Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Oral, Category 4
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |   |
|---|---|
| Signal word | Warning |
| Hazard statement(s) | H302 Harmful if swallowed H411 Toxic to aquatic life with long lasting effects |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P273 Avoid release to the environment. |
| Response | P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P391 Collect spillage. |
| Storage | none |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
3.Composition/information on ingredients
3.1 Substances
| Chemical name | Common names and synonyms | CAS number | EC number | Concentration |
|---|---|---|---|---|
| 1,3-dichlorobenzene | 1,3-dichlorobenzene | 541-73-1 | none | 100% |
4.First-aid measures
4.1 Description of necessary first-aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
Fresh air, rest. Refer for medical attention.
In case of skin contact
Remove contaminated clothes. Rinse skin with plenty of water or shower. Refer for medical attention .
In case of eye contact
First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.
If swallowed
Rinse mouth. Refer for medical attention .
4.2 Most important symptoms/effects, acute and delayed
INHALATION: Causes headache, drousiness, unsteadiness. Irritating to mucous membranes. EYES: Severe irritation. SKIN: Severe irritation. INGESTION: Irritation of gastric mucosa, nausea, vomiting, diarrhea, abdominal cramps and cyanosis. (USCG, 1999)
4.3 Indication of immediate medical attention and special treatment needed, if necessary
/SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Lindane and related compounds/
5.Fire-fighting measures
5.1 Extinguishing media
Suitable extinguishing media
WATER, FOAM, CARBON DIOXIDE, DRY CHEM ...
5.2 Specific hazards arising from the chemical
Special Hazards of Combustion Products: Irritating vapors including hydrogen chloride are produced. (USCG, 1999)
5.3 Special protective actions for fire-fighters
Wear self-contained breathing apparatus for firefighting if necessary.
6.Accidental release measures
6.1 Personal precautions, protective equipment and emergency procedures
Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.
6.2 Environmental precautions
Personal protection: filter respirator for organic gases and particulates adapted to the airborne concentration of the substance. Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.
6.3 Methods and materials for containment and cleaning up
Environmental considerations: Land spill: Dig a pit, pond, lagoon, holding area to contain liquid or solid material. Dike surface flow using soil, sand bags, foamed polyurethane, or foamed concrete. Absorb bulk liquid with fly ash or cement powder. Apply "universal" gelling agent to immobilize spill. /SRP: If time permits, pits, ponds, lagoons, soak holes, or holding areas should be sealed with an impermeable flexible membrane liner./ /o-Dichlorobenzene/ Cover solids with a plastic sheet to prevent dissolving in rain or fire fighting water. /p-Dichlorobenzene/
7.Handling and storage
7.1 Precautions for safe handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.
7.2 Conditions for safe storage, including any incompatibilities
Provision to contain effluent from fire extinguishing. Separated from strong oxidants, aluminium and food and feedstuffs. Well closed. Store in an area without drain or sewer access.
8.Exposure controls/personal protection
8.1 Control parameters
Occupational Exposure limit values
no data available
Biological limit values
no data available
8.2 Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.
8.3 Individual protection measures, such as personal protective equipment (PPE)
Eye/face protection
Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).
Skin protection
Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.
Respiratory protection
Wear dust mask when handling large quantities.
Thermal hazards
no data available
9.Physical and chemical properties
| Physical state | Colorless to yellowish liquid with Aromatic odor. |
|---|---|
| Colour | Colorless liquid |
| Odour | no data available |
| Melting point/ freezing point | -24oC |
| Boiling point or initial boiling point and boiling range | 172-173oC |
| Flammability | Combustible. Gives off irritating or toxic fumes (or gases) in a fire. |
| Lower and upper explosion limit / flammability limit | no data available |
| Flash point | 67oC |
| Auto-ignition temperature | 647.78°C (USCG, 1999) |
| Decomposition temperature | no data available |
| pH | no data available |
| Kinematic viscosity | 1.044 mPa.s at 25°C |
| Solubility | In water:0.0123 g/100 mL (25 oC) |
| Partition coefficient n-octanol/water (log value) | log Kow = 3.53 |
| Vapour pressure | 5 mm Hg ( 38.8 °C) |
| Density and/or relative density | 1.288 |
| Relative vapour density | 5.08 (Relative to Air) |
| Particle characteristics | no data available |
10.Stability and reactivity
10.1 Reactivity
no data available
10.2 Chemical stability
Stable under recommended storage conditions.
10.3 Possibility of hazardous reactions
CombustibleThe vapour is heavier than air.M-DICHLOROBENZENE is incompatible with oxidizing agents and aluminum and its alloys. Above the flash point, explosive vapor-air mixtures may be formed.
10.4 Conditions to avoid
no data available
10.5 Incompatible materials
CAN REACT VIOLENTLY WITH ALUMINUM ...
10.6 Hazardous decomposition products
When heated to decomposition it emits toxic /hydrogen chloride/ fumes.
11.Toxicological information
Acute toxicity
- Oral: LD50 Rat (Sprague-Dawley male) oral (gavage) 1,200 mg/kg
- Inhalation: LC50 Rat inhalation >17.6 mg/L/4 hr
- Dermal: no data available
Skin corrosion/irritation
no data available
Serious eye damage/irritation
no data available
Respiratory or skin sensitization
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
NTP: Reasonably anticipated to be a human carcinogen
Reproductive toxicity
no data available
STOT-single exposure
no data available
STOT-repeated exposure
no data available
Aspiration hazard
no data available
12.Ecological information
12.1 Toxicity
- Toxicity to fish: LC50; Species: Danio rerio (Zebra danio, adult ~9 months, weight 0.8 g, length 4.3 cm); Conditions: freshwater, static, 24°C, pH 7.8, hardness 350 mg/L CaCO3; Concentration: 148 mg/L for 96 hr /99% purity
- Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea); Conditions: freshwater, renewal, 25°C, pH >7; Concentration: 7 mg/L for 24 hr; Effect: behavior, equilibrium
- Toxicity to algae: EC50; Species: Scenedesmus subspicatus (Green algae, log growth phase); Conditions: freshwater, static, 24°C, pH 8.0-9.3; Concentration: 19000 ug/L for 48 hr; Effect: population biomass
- Toxicity to microorganisms: no data available
12.2 Persistence and degradability
AEROBIC: 1,3-Dichlorobenzene at 100 mg/L exhibited 0% of its theoretical BOD using an activated sludge inoculum at 30 mg/L over a 4 week incubation period in the Japanese MITI test(1). Dichlorobenzene isomers were slowly biodegraded (6.3% of theoretical CO2 evolution in 10 weeks) in an alkaline soil sample(2).
12.3 Bioaccumulative potential
BCF values of 60 to 230 were measured in carp exposed to 100 ug/L of 1,3-dichlorobenzene during an 8 week incubation period and BCF values of 60 to 370 were measured in carp exposed to 10 ug/L of 1,3-dichlorobenzene during an 8 week incubation period(1). Mean 1,3-dichlorobenzene BCF values of 420 to 740 were experimentally determined for rainbow trout exposed up to 119 days in laboratory aquaria(2). A whole body BCF of 90 was determined for bluegill sunfish exposed to 1,3-dichlorobenzene over a 28-day period in a continuous flow system(3). According to a classification scheme(4), these BCF values suggest that bioconcentration in aquatic organisms is moderate to high.
12.4 Mobility in soil
An experimental Koc value of 300(1) was determined for 1,3-dichlorobenzene in silt loam soil. According to a recommended classification scheme(3), these Koc values suggest that 1,3-dichlorobenzene has moderate to low mobility in soil. A log Koc value of 3.5 was reported for 1,3-dichlorobenzene in sediment obtained from the Ise Bay, Japan(2) and a log Koc value of 4.7 was measured from sediment of Lake Ketelmeer, Netherlands(4).
12.5 Other adverse effects
no data available
13.Disposal considerations
13.1 Disposal methods
Product
The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.
Contaminated packaging
Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.
14.Transport information
14.1 UN Number
| ADR/RID: UN9255 | IMDG: UN9255 | IATA: UN9255 |
14.2 UN Proper Shipping Name
| ADR/RID: unknown |
| IMDG: unknown |
| IATA: unknown |
14.3 Transport hazard class(es)
| ADR/RID: 9 | IMDG: 9 | IATA: 9 |
14.4 Packing group, if applicable
| ADR/RID: III | IMDG: III | IATA: III |
14.5 Environmental hazards
| ADR/RID: yes | IMDG: yes | IATA: yes |
14.6 Special precautions for user
no data available
14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code
no data available
15.Regulatory information
15.1 Safety, health and environmental regulations specific for the product in question
| Chemical name | Common names and synonyms | CAS number | EC number |
|---|---|---|---|
| 1,3-dichlorobenzene | 1,3-dichlorobenzene | 541-73-1 | none |
| European Inventory of Existing Commercial Chemical Substances (EINECS) | Listed. | ||
| EC Inventory | Listed. | ||
| United States Toxic Substances Control Act (TSCA) Inventory | Listed. | ||
| China Catalog of Hazardous chemicals 2015 | Listed. | ||
| New Zealand Inventory of Chemicals (NZIoC) | Listed. | ||
| Philippines Inventory of Chemicals and Chemical Substances (PICCS) | Listed. | ||
| Vietnam National Chemical Inventory | Listed. | ||
| Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) | Listed. | ||
16.Other information
Information on revision
| Creation Date | Aug 17, 2017 |
|---|---|
| Revision Date | Aug 17, 2017 |
Abbreviations and acronyms
- CAS: Chemical Abstracts Service
- ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
- RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
- IMDG: International Maritime Dangerous Goods
- IATA: International Air Transportation Association
- TWA: Time Weighted Average
- STEL: Short term exposure limit
- LC50: Lethal Concentration 50%
- LD50: Lethal Dose 50%
- EC50: Effective Concentration 50%
References
- IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
- HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
- IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
- eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
- CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
- ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
- ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
- Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
- ECHA - European Chemicals Agency, website: https://echa.europa.eu/
