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2,2-Bis(p-methoxyphenol)-1,1,1 -trich loroethane SDS

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SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name methoxychlor

1.2 Other means of identification

Product number -
Other names 1-methoxy-4-[2,2,2-trichloro-1-(4-methoxyphenyl)ethyl]benzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Pesticides (chemicals used for killing pests, such as rodents, insects, or plants)
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Specific target organ toxicity – single exposure, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H302 Harmful if swallowed

H371 May cause damage to organs

H400 Very toxic to aquatic life

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.

Response

P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell.

P330 Rinse mouth.

P308+P311 IF exposed or concerned: Call a POISON CENTER/doctor/...

P391 Collect spillage.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
methoxychlor methoxychlor 72-43-5 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest.

In case of skin contact

Remove contaminated clothes. Rinse and then wash skin with water and soap.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Induce vomiting (ONLY IN CONSCIOUS PERSONS!). Give one or two glasses of water to drink. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

Toxicity is relatively low. Inhalation or ingestion causes generalized depression. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Observation. Persons exposed to high levels of organochlorine pesticides by any route should be observed for sensory disturbances, incoordination, speech slurring, mental aberrations, and involuntary motor activity that would warn of imminent convulsions. /Solid organochlorine insecticides/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Water, foam, dry chemical, or carbon dioxide.

5.2 Specific hazards arising from the chemical

Special Hazards of Combustion Products: Irritating and toxic hydrogen chloride gas may be formed in fire. (USCG, 1999)

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into sealable containers. If appropriate, moisten first to prevent dusting. Carefully collect remainder. Then store and dispose of according to local regulations. Do NOT let this chemical enter the environment.

6.3 Methods and materials for containment and cleaning up

SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a POTW is acceptable only after review by the governing authority. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must meet Hazardous Material Criteria for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Separated from food and feedstuffs. Well closed. Keep in a well-ventilated room.Storage temperature: ambient

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

NIOSH considers methoxychlor to be a potential occupational carcinogen.

NIOSH usually recommends that occupational exposures to carcinogens be limited to the lowest feasible concentration.

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state COLOURLESS TO LIGHT YELLOW CRYSTALS , WITH CHARACTERISTIC ODOUR.
Colour Colorless crystals (technical, grey powder)
Odour Slight, fruity odor
Melting point/ freezing point 86-88oC(lit.)
Boiling point or initial boiling point and boiling range greater than or equal to 100oC.
Flammability Combustible Solid, but difficult to burn.Combustible. Liquid formulations containing organic solvents may be flammable. Gives off irritating or toxic fumes (or gases) in a fire.
Lower and upper explosion limit / flammability limit no data available
Flash point less than 60 degreesoC
Auto-ignition temperature no data available
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility less than 1 mg/mL at 22.78°C
Partition coefficient n-octanol/water (log value) log Kow = 5.08
Vapour pressure Very low
Density and/or relative density 1.4 g/cm3
Relative vapour density 12 (Relative to Air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable to UV light.

10.3 Possibility of hazardous reactions

The material is a combustible solid, but difficult to ignite.METHOXYCHLOR turns pink or tan on exposure to light. This chemical is incompatible with alkaline materials, especially in the presence of catalytically-active metals. It is slightly corrosive to iron and aluminum. It is decomposed by refluxing with sodium in isopropyl alcohol. It is also incompatible with strong oxidizers. It will attack some forms of plastics, rubber and coatings. .

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Contact with strong oxidizers may cause fires and explosions.

10.6 Hazardous decomposition products

... When heated to decomp, it emits highly toxic fumes of /hydrogen chloride/ .

11.Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 6000 mg/kg /Technical material/
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

Classification of carcinogenicity: 1) evidence in humans: no data; 2) evidence in animals: insufficient. Overall summary evaluation of carcinogenic risk to humans is Group 3: The agent is not classifiable as to its carcinogenicity to humans. /From table/

Reproductive toxicity

No information is available on the reproductive or developmental effects of methoxychlor in humans. Methoxychlor and its metabolites possess estrogenic properties. Reproductive and developmental effects have been reported in animals orally exposed to methoxychlor. (4,6) Effects to the development of the female reproductive system, gross and histopathological changes in the male and female reproductive systems, effects on male and female reproductive function (i.e., decreased fertility in males and females, decreased spermatogenesis, and interference with estrus cycling), and changes to hormone levels have been reported in orally exposed animals. (4) In rabbits orally exposed to methoxychlor, excessive loss of litters (abortions) was observed. (6) Skeletal effects were observed in the offspring of rats exposed to methoxychlor by gavage (experimentally placing the chemical in the stomach). (4,6) Long-term oral exposure to methoxychlor has been reported to increase fetotoxicity in animals, as well as to affect the reproductive development and reduce the fertility of offspring. (4,6)

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50; Species: Lepomis macrochirus (Bluegill, weight 0.6 g); Conditions: freshwater, flow through, 18°C, pH 7.4, hardness 272 mg/L CaCO3; Concentration: 100 ug/L for 24 hr (95% confidence limit 62-162 ug/L) /98% purity, technical material
  • Toxicity to daphnia and other aquatic invertebrates: EC50; Species: Daphnia magna (Water flea, age <24 hr); Conditions: freshwater, static; Concentration: 1800 ug/L for 48 hr (95% confidence interval: 1500-2100 ug/L); Effect: intoxication, immobilization /40% purity
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: First-order rate constants of 0.001 to 0.004 (half-life of 7 to 29 days), 0.002 to 0.003 (half-life of 9.6 to 14.4 days), 0.001 to 0.006 (half-life of 4.8 to 29 days), and 0.002 to 0.004 per hour (half-life of 7 to 14.4 days) were measured for methoxychlor added to 4 different freshwaters(1). In an aerobic die-away study using water from the Santa Rosa Sound, FL, methoxychlor had a half-life of >25 days(2). In an aerobic shake-flask river die-away test, methoxychlor was biodegraded in a mixed water/sediment sample, rate not given(3). The degradation of methoxychlor in 2 sandy loam soils was dependent on water content; soils with 3% and 10% water content degraded methoxychlor to only trace amounts within 30 to 38 and 20 to 26 weeks, respectively(4). Methoxychlor applied to soil during a 2-year field study was fairly persistent; residues remaining after 1, 2, and 3 months made up 92, 38, and 27% of the original application(5). One year later, measurable concentrations of methoxychlor were still present in soil as well as products from the partial dechlorination of the parent compound(5). Second-order rate constants of 5.2X10-14 and 6.1X10-16 liters per organism-hr (half-lives of 111 and 9500 days, respectively, assuming a bacterial concentration of 5X10+9 organisms/L) were measured dependent on 15% and 90% sorption, respectively, to sediments in river die-away studies(6).

12.3 Bioaccumulative potential

Bioconcentration factors (BCF) for methoxychlor of 8300 in fathead minnow (Pimephales promelas)(1) and 138 in sheepshead minnow (Cyprinodon variegatus)(4) have been measured in continuous flow systems. According to a classification scheme(6), these BCF values suggest that bioconcentration in aquatic organisms is high to very high(SRC). However, as seen in the BCF from the sheepshead minnow study, some variation between species in the ability to metabolize this compound may exist(7-9). Bioconcentration factors (BCF) for methoxychlor of 12,000 in mussel(2), 5000-8570 in snail (Physa integra), 348-1130 in stonefly (Pteronarcys dorsata)(3) and 1500 in soft clams (Mya avenaria)(5) have also been measured in continuous flow systems.

12.4 Mobility in soil

Measured average sorption coefficient (Koc) values in various pond and river sediments are as follows: 23,000 in sand, 82,000 in coarse silt, 88,000 in medium silt, 93,000 in fine silt and 83,000 in clay(1). In another study, a K value of 620 was found in a water-sediment system(2). Another study determined a K value of 2009 in soil(3). According to a classification scheme(4), these Koc values suggest that methoxychlor is expected to be immobile in soil. Mass balances in pond, river and wet sand (25% moisture) systems spiked with methoxychlor indicate that 98.6, 97.0, and 92.1%, respectively, of all methoxychlor was retained in the sediment(5).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN2811 IMDG: UN2811 IATA: UN2811

14.2 UN Proper Shipping Name

ADR/RID: TOXIC SOLID, ORGANIC, N.O.S.
IMDG: TOXIC SOLID, ORGANIC, N.O.S.
IATA: TOXIC SOLID, ORGANIC, N.O.S.

14.3 Transport hazard class(es)

ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1

14.4 Packing group, if applicable

ADR/RID: III IMDG: III IATA: III

14.5 Environmental hazards

ADR/RID: yes IMDG: yes IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
methoxychlor methoxychlor 72-43-5 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Not Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Not Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Not Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 18, 2017
Revision Date Aug 18, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
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