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2-Chloro-5-iodopyrazine is a heterocyclic organic compound characterized by the chemical formula C4H2ClIN2. It is a halogenated derivative of pyrazine, known for its unique chemical properties that make it a valuable building block in the synthesis of pharmaceuticals and agrochemicals. 2-Chloro-5-iodopyrazine is distinguished by its ability to participate in nucleophilic substitution reactions and its potential for metal-catalyzed cross-coupling reactions, which are of significant interest to researchers and industries in the development of innovative molecules for drug development and crop protection.

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  • 1057216-55-3 Structure
  • Basic information

    1. Product Name: 2-Chloro-5-iodopyrazine
    2. Synonyms: 2-Chloro-5-iodopyrazine
    3. CAS NO:1057216-55-3
    4. Molecular Formula: C4H2ClIN2
    5. Molecular Weight: 240.42955
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1057216-55-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 0.0348 mmHg at 25 °C
    3. Flash Point: 105.1 °C
    4. Appearance: /
    5. Density: 2.187 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. PKA: -4.25±0.10(Predicted)
    10. CAS DataBase Reference: 2-Chloro-5-iodopyrazine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-Chloro-5-iodopyrazine(1057216-55-3)
    12. EPA Substance Registry System: 2-Chloro-5-iodopyrazine(1057216-55-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1057216-55-3(Hazardous Substances Data)

1057216-55-3 Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-5-iodopyrazine is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to undergo nucleophilic substitution and cross-coupling reactions, which are crucial for the creation of novel drug molecules with potential therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Chloro-5-iodopyrazine serves as a vital component in the development of new agrochemicals, leveraging its reactivity in organic synthesis to produce compounds with effective pest control and crop protection properties.
Used in Organic Synthesis:
2-Chloro-5-iodopyrazine is utilized as a versatile building block in organic synthesis, taking advantage of its unique chemical properties to create a wide range of organic compounds for various applications, including but not limited to, the development of new materials, dyes, and other specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 1057216-55-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,7,2,1 and 6 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1057216-55:
(9*1)+(8*0)+(7*5)+(6*7)+(5*2)+(4*1)+(3*6)+(2*5)+(1*5)=133
133 % 10 = 3
So 1057216-55-3 is a valid CAS Registry Number.

1057216-55-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Chloro-5-iodopyrazine

1.2 Other means of identification

Product number -
Other names 2-Chloro-5-iodo-pyrazine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1057216-55-3 SDS

1057216-55-3Upstream product

1057216-55-3Relevant articles and documents

Aryl sulfonamide and sulfonyl compounds as modulators of PPAR and methods of treating metabolic disorders

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Page/Page column 70, (2010/02/14)

Aryl sulfonamide and sulfonyl compounds as modulators of peroxisome proliferator activated receptors, pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.

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