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2-Methoxy-3-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine is a pyridine derivative featuring a methoxy and a methyl group at the 2 and 3 positions, respectively, and a boron-containing heterocycle at the 5 position. This chemical compound is predominantly utilized as a reagent in organic synthesis, playing a crucial role in the formation of carbon-carbon and carbon-heteroatom bonds through various catalytic and cross-coupling reactions. Its unique structure renders it a valuable building block in organic chemistry, with applications extending to the synthesis of pharmaceuticals, agrochemicals, and materials.

1083168-83-5

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  • 2-METHOXY-3-METHYL-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)-PYRIDINE

    Cas No: 1083168-83-5

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1083168-83-5 Usage

Uses

Used in Organic Synthesis:
2-Methoxy-3-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine is used as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds, facilitating various catalytic and cross-coupling reactions. Its ability to participate in these reactions is instrumental in the synthesis of complex organic molecules.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, 2-Methoxy-3-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine is used as a key intermediate in the synthesis of various drugs. Its unique structure allows for the creation of novel compounds with potential therapeutic properties.
Used in Agrochemical Synthesis:
Similarly, in agrochemical applications, 2-Methoxy-3-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine serves as a building block for the development of new agrochemicals, such as pesticides and herbicides, contributing to enhanced crop protection strategies.
Used in Material Science:
2-Methoxy-3-methyl-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-pyridine is also utilized in material science for the synthesis of advanced materials with specific properties, such as conductivity, stability, or reactivity, which can be applied in various technological and industrial processes.

Check Digit Verification of cas no

The CAS Registry Mumber 1083168-83-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,8,3,1,6 and 8 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1083168-83:
(9*1)+(8*0)+(7*8)+(6*3)+(5*1)+(4*6)+(3*8)+(2*8)+(1*3)=155
155 % 10 = 5
So 1083168-83-5 is a valid CAS Registry Number.

1083168-83-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-methoxy-3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine

1.2 Other means of identification

Product number -
Other names 6-METHOXY-5-METHYLPYRIDINE-3-BORONIC ACID PINACOL ESTER

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1083168-83-5 SDS

1083168-83-5Relevant articles and documents

NOVEL TRICYCLIC COMPOUNDS

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Page/Page column 74, (2019/05/15)

This invention relates to certain novel tricyclic compounds as bromodomain and extra-terminal (BET) inhibitors, their synthesis and their use for treating diseases. More particularly, this invention is directed to fused heterocyclic derivatives useful as

TOLL-LIKE RECEPTOR 8 (TLR8)-SPECIFIC ANTAGONISTS AND METHODS OF MAKING AND USES THEREOF

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Page/Page column 49-50; 74, (2019/05/22)

Toll-like receptor 8 (TLR8)-specific inhibitors and methods of using the same in individuals having an autoimmune disease or an inflammatory disorder.

Use of Inhibitors of the Activity or Function of PI3K

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Paragraph 0863-0868, (2016/01/09)

The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.

QUINAZOLINE DERIVATIVES AS PI3K MODULATORS

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Page/Page column 50-51, (2013/05/09)

The invention relates to substituted quinazoline derivative of the formula (I), wherein A, X1, X2, X3, X4 and R5 are as defined in the description. Such compounds are suitable for the treatment of a disorder or disease which is mediated by the activity of the PI3K enzymes.

Use of inhibitors of the activity or function of PI3K

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Page/Page column 97; 98, (2013/07/05)

The invention relates to new uses of PI3K inhibitors, wherein said inhibitors have an inhibitory action on the PI3K isoform delta for the treatment of immunopathology in a subject suffering from a disease or disorder selected from malaria, leishmaniasis, trypanosomiasis, toxoplasmosis and/or neurocysticercosis, via functional inhibition of TLR9 of the infected subject.

MODULATORS OF CFTR

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Page/Page column 100-101, (2009/01/20)

Compounds of the present invention, and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette ("ABC") transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator ("CFTR"). The present invention also relates to methods of treating CFTR mediated diseases using compounds of the present invention.

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