1138331-74-4 Usage
Uses
Used in Pharmaceutical Industry:
2-Bromo-4-(trifluoromethoxy)benzonic acid is used as a key intermediate for the synthesis of Sulfinylaminobenzamide and Sulfonylaminobenzamide derivatives. These derivatives serve as mitochondrial oxidative phosphorylation uncouplers, which are important in the development of drugs targeting various diseases and conditions related to cellular energy metabolism.
In the pharmaceutical industry, 2-Bromo-4-(trifluoromethoxy)benzonic acid plays a crucial role in the development of novel therapeutic agents that can potentially modulate cellular energy production and disrupt the energy balance in disease-causing cells, thereby inhibiting their growth and proliferation. This application is particularly relevant in the research and development of treatments for cancer, neurodegenerative diseases, and other conditions where mitochondrial dysfunction is implicated.
Check Digit Verification of cas no
The CAS Registry Mumber 1138331-74-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,3,8,3,3 and 1 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1138331-74:
(9*1)+(8*1)+(7*3)+(6*8)+(5*3)+(4*3)+(3*1)+(2*7)+(1*4)=134
134 % 10 = 4
So 1138331-74-4 is a valid CAS Registry Number.
1138331-74-4Relevant articles and documents
SUBSTITUTED ARYL SULFONE DERIVATIVES AS CALCIUM CHANNEL BLOCKERS
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Page/Page column 40, (2009/05/29)
A series of substituted aryl sulfone derivatives represented by Formula I, or pharmaceutically acceptable salts thereof. Pharmaceutical compositions comprise an effective amount of the instant compounds, either alone, or in combination with one or more other therapeutically active compounds, and a pharmaceutically acceptable carrier. Methods of treating conditions associated with, or caused by, calcium channel activity, including, for example, acute pain, chronic pain, visceral pain, inflammatory pain, neuropathic pain, urinary incontinence, itchiness, allergic dermatitis, epilepsy, diabetic neuropathy, irritable bowel syndrome, depression, anxiety, multiple sclerosis, sleep disorder, bipolar disorder and stroke, comprise administering an effective amount of the present compounds, either alone, or in combination with one or more other therapeutically active compounds.
