1186410-71-8

• 

• Basic information

  1. Product Name: 2,4-dichloro-5,6-dihydrobenzo[h]quinazoline
  2. Synonyms:
  3. CAS NO:1186410-71-8
  4. Molecular Formula:
  5. Molecular Weight: 251.115
  6. EINECS: N/A
  7. Product Categories: N/A
  8. Mol File: 1186410-71-8.mol

• Chemical Properties

  1. Melting Point: N/A
  2. Boiling Point: N/A
  3. Flash Point: N/A
  4. Appearance: N/A
  5. Density: N/A
  6. Refractive Index: N/A
  7. Storage Temp.: N/A
  8. Solubility: N/A
  9. CAS DataBase Reference: 2,4-dichloro-5,6-dihydrobenzo[h]quinazoline(CAS DataBase Reference)
  10. NIST Chemistry Reference: 2,4-dichloro-5,6-dihydrobenzo[h]quinazoline(1186410-71-8)
  11. EPA Substance Registry System: 2,4-dichloro-5,6-dihydrobenzo[h]quinazoline(1186410-71-8)

• Safety Data

  1. Hazard Codes: N/A
  2. Statements: N/A
  3. Safety Statements: N/A
  4. WGK Germany:
  5. RTECS:
  6. HazardClass: N/A
  7. PackingGroup: N/A
  8. Hazardous Substances Data: 1186410-71-8(Hazardous Substances Data)

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• Upstream product
• Downstream Products
• Article

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• 2,4-Dichloro-5,6-dihydrobenzo[h]quinazoline

  Cas No: 1186410-71-8

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• 2,4-dichloro-5,6-dihydrobenzo[h]quinazoline

  Cas No: 1186410-71-8

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1186410-71-8 Usage

Physical Appearance

White to off-white crystalline powder

Solubility

Sparingly soluble in water

Primary Use

Building block in chemical synthesis

Industry Application

Pharmaceutical industry

Potential Applications

Antiviral drug development
Antibacterial drug development
Antifungal drug development
Antitumor agent research

Academic Research Use

Starting material for developing compounds with biological activities

Check Digit Verification of cas no

The CAS Registry Mumber 1186410-71-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,6,4,1 and 0 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1186410-71:
(9*1)+(8*1)+(7*8)+(6*6)+(5*4)+(4*1)+(3*0)+(2*7)+(1*1)=148
148 % 10 = 8
So 1186410-71-8 is a valid CAS Registry Number.

1186410-71-8Upstream product

• 7442-52-6 methyl 1-oxo-1,2,3,4-tetrahydronaphthalene-2-carboxylate 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 236093-45-1 5,6-dihydrobenzo[h]quinazoline-2,4(1H,3H)-dione 

1186410-71-8Downstream Products

1186410-71-8Relevant articles and documents

2,4-Diaminopyrimidines as dual ligands at the histamine H1 and H4 receptor - H1/H4-receptor selectivity

Hammer, Sebastian G.,Gobleder, Susanne,Naporra, Franziska,Wittmann, Hans-Joachim,Elz, Sigurd,Heinrich, Markus R.,Strasser, Andrea

, p. 292 - 300 (2016/01/09)

Distinct diaminopyrimidines, for example, 4-(4-methylpiperazin-1-yl)-5,6-dihydrobenzo[h]quinazolin-2-amine are histamine H4 receptor (H4R) antagonists and show high affinity to the H4R, but only a moderate affinity to the

1,2,4-TRIAZOLO[4,3-C]PYRIMIDIN-3-ONE AND PYRAZOLO [4,3-E] -1,2,4-TRIAZOLO [4,3-C] PYRIMIDIN-3-ONE COMPOUNDS FOR USE AS ADENOSINE A2A RECEPTOR ANTAGONISTS

-

Page/Page column 36-37, (2009/10/22)

Compounds of the Formula I wherein R1 and R2 together with the carbon atoms to which they are bonded optionally form a further heteroaromatic ring of the formula (II) as well as pharmaceutically acceptable salts, solvates, esters and

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