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(R)-1-(3,5-DiMethoxyphenyl)ethanamine, also known as R-DMA, is a substituted phenethylamine and a psychoactive drug. It is a derivative of amphetamine with both hallucinogenic and stimulant effects. R-DMA functions as a potent agonist of the 5-HT2A receptor and a reuptake inhibitor of serotonin and norepinephrine, which contribute to its psychoactive properties. (R)-1-(3,5-DiMethoxyphenyl)ethanaMine has been studied for its potential therapeutic effects in treating depression and anxiety, but its recreational use poses serious health risks and potential for abuse.

1241676-71-0

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1241676-71-0 Usage

Uses

Used in Pharmaceutical Research:
R-DMA is used as a research compound for its potential therapeutic effects in treating depression and anxiety. Its action as a serotonin and norepinephrine reuptake inhibitor, along with its agonist effect on the 5-HT2A receptor, makes it a subject of interest for the development of novel treatments for mood disorders.
Used in Neuroscientific Studies:
In the field of neuroscience, R-DMA is utilized as a research tool to study the mechanisms of action of hallucinogenic substances and their effects on the brain. Understanding its interaction with the 5-HT2A receptor can provide insights into the role of serotonin in mood regulation and perception.
Used in Drug Abuse Prevention and Education:
R-DMA is also used in the context of drug abuse prevention and education to raise awareness about the serious health risks and potential for abuse associated with its recreational use. Educating the public and professionals about the dangers of using psychoactive substances like R-DMA is crucial for promoting safe and responsible behavior.

Check Digit Verification of cas no

The CAS Registry Mumber 1241676-71-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,4,1,6,7 and 6 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1241676-71:
(9*1)+(8*2)+(7*4)+(6*1)+(5*6)+(4*7)+(3*6)+(2*7)+(1*1)=150
150 % 10 = 0
So 1241676-71-0 is a valid CAS Registry Number.

1241676-71-0Downstream Products

1241676-71-0Relevant articles and documents

ISOQUINOLINE COMPOUNDS, A PROCESS FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

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Paragraph 0288; 0291; 0292; 0960; 961; 0962, (2017/06/12)

A compound of formula (I): wherein the substituents are as defined in the description. Medicinal products containing the same which are useful in treating or preventing pathologies which are the result of activation of the RhoA/ROCK pathway and phosphorylation of the myosin light chain.

SUBSTITUTED ARYLAMINE COMPOUNDS AND THEIR USE AS 5-HT6 MODULATORS

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Page/Page column 73-74, (2008/06/13)

The invention relates to 5-HT6 receptor antagonists. Novel arylamine compounds having the formula: (see formula I) and pharmaceutically acceptable salts and/or esters thereof, wherein - n is 0, 1, 2, 3, or 4; - A, when present is a lower alkyl

Chiral Building Blocks for the Synthesis of Nitrogen-Containing Natural Products, 5. The Enantioselective Synthesis of Optically Active, Benzene Nucleus-Substituted 1-Phenylethylamines from the Corresponding Acetophenones

Bringmann, Gerhard,Geisler, Joerg-Peter,Geuder, Torsten,Kuenkel, Georg,Kinzinger Lioba

, p. 795 - 805 (2007/10/02)

An efficient two-step procedure for the synthesis of enantiomerically pure, benzene nucleus-substituted 1-phenylethylamines 1 is described, with predictable absolute configuration at the stereogenic center: Imine formation from the substituted acetophenones 6 with (S)- or (R)-1-phenylethylamine and subsequent hydrogenation of the resulting Schiff bases 8 over Raney nickel leads to the secondary amines 9 and 10 in high diastereoselectivities.These dibenzylamines are cleaved regioselectively, usually next to the less substituted aromatic ring, giving the desired chiral 1-phenylethylamines 1 in high yields and enantiomeric purities.Scope and limitations of this new and facile approach to the versatile building blocks 1 are reported.

Synthesis and activity of 5-(aminomethylene)-1,3-cyclohexanediones: Enolic analogues of γ-aminobutyric acid

Mann,Humblet,Chambon,Schlichter,Desarmenien,Feltz,Wermuth

, p. 1440 - 1446 (2007/10/02)

Eight 1,3-cyclohexanediones with an aminoalkyl side chain in the 5-position were synthesized as rigid enolic analogues of GABA (γ-aminobutyric acid). Biochemical investigations about their abilities to displace [3H]GABA and [3H]baclo

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