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(R)-BHPphos, also known as (R)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl, is a chiral phosphine ligand that plays a crucial role in asymmetric synthesis reactions. It is widely recognized for its high reactivity and selectivity, making it an indispensable component in the development of transition metal-catalyzed asymmetric hydrogenation. This method is particularly valuable for the synthesis of chiral compounds, which are essential in the production of pharmaceuticals and other fine chemicals. The unique structure and properties of (R)-BHPphos contribute significantly to its effectiveness in the field of organic chemistry, particularly in the creation of optically pure compounds.

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  • (11bR)?-N-?(Diphenylmethyl)?-?N-?phenyl-?dinaphtho[2,?1-?d:1',?2'-?f]?[1,?3,?2]?dioxaphosphepin-?4-?amine

    Cas No: 1360145-10-3

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  • 1360145-10-3 Structure
  • Basic information

    1. Product Name: (R)-BHPphos
    2. Synonyms: (R)-BHPphos;(11bR)-N-(Diphenylmethyl)-N-phenyl-dinaphtho[2,1-d:1', 2'-f][1,3,2]dioxaphosphepin-4-amine
    3. CAS NO:1360145-10-3
    4. Molecular Formula: C39H28NO2P
    5. Molecular Weight: 573.618881
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1360145-10-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 757.4±70.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 0.02±0.20(Predicted)
    10. CAS DataBase Reference: (R)-BHPphos(CAS DataBase Reference)
    11. NIST Chemistry Reference: (R)-BHPphos(1360145-10-3)
    12. EPA Substance Registry System: (R)-BHPphos(1360145-10-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: 24/25
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1360145-10-3(Hazardous Substances Data)

1360145-10-3 Usage

Uses

Used in Pharmaceutical Industry:
(R)-BHPphos is used as a chiral ligand for the synthesis of chiral compounds, which are vital in the development of pharmaceuticals. Its high reactivity and selectivity enable the production of optically pure compounds, which are essential for the effectiveness, safety, and quality of many medications.
Used in Fine Chemicals Industry:
(R)-BHPphos is used as a key component in the synthesis of fine chemicals, which are high-purity chemicals used in various applications, including the production of specialty materials, fragrances, and flavors. Its ability to facilitate the creation of optically pure compounds makes it a valuable asset in this industry.
Used in Organic Chemistry Research:
(R)-BHPphos is used as a research tool in the field of organic chemistry, particularly in the study of asymmetric synthesis and the development of new methods for the production of chiral compounds. Its unique structure and properties make it an ideal candidate for exploring new reaction pathways and improving existing synthetic processes.
Used in Transition Metal-Catalyzed Asymmetric Hydrogenation:
(R)-BHPphos is used as a ligand in the transition metal-catalyzed asymmetric hydrogenation process, which is a valuable method for synthesizing chiral compounds. Its high reactivity and selectivity contribute to the efficiency and effectiveness of this process, making it a popular choice for chemists working in this area.

Check Digit Verification of cas no

The CAS Registry Mumber 1360145-10-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,6,0,1,4 and 5 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1360145-10:
(9*1)+(8*3)+(7*6)+(6*0)+(5*1)+(4*4)+(3*5)+(2*1)+(1*0)=113
113 % 10 = 3
So 1360145-10-3 is a valid CAS Registry Number.

1360145-10-3Upstream product

1360145-10-3Downstream Products

1360145-10-3Relevant articles and documents

N-aryl of containing compound chiral phosphine nitrogen, synthetic method and application

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Paragraph 0045-0048, (2016/10/07)

The invention provides a chirality phosphine nitrogen compound containing N-aryl as well as a synthetic method and application thereof. The phosphine nitrogen compound is based on axial chirality or comprises a helical chirality skeleton, and is synthetiz

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