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1370261-97-4

PRT062607 (Hydrochloride) is a compound that serves as a novel spleen tyrosine kinase (SYK) inhibitor. It is characterized by its ability to inhibit the activity of SYK, a protein that plays a crucial role in various cellular processes, including immune response and cell signaling. By targeting SYK, PRT062607 (Hydrochloride) has the potential to modulate these processes and offer therapeutic benefits in certain medical conditions.

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  • 1370261-97-4 Structure

  • Basic information

    1. Product Name: PRT062607 (Hydrochloride)
    2. Synonyms: PRT062607 (Hydrochloride);PRT062607 (P505-15, BIIB057) HCl;2-[[(1R,2S)-2-AMinocyclohexyl]aMino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]aMino]-5-pyriMidinecarboxaMide Hydrochloride;PRT062607 (P505-15 HCL);PRT062607 HCL;2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide hydrochloride (1:1);5-Pyrimidinecarboxamide, 2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-, hydrochloride (1:1);2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide hydrochloride (1:1) PRT062607 (P505-15, BIIB057) HCl
    3. CAS NO:1370261-97-4
    4. Molecular Formula: C19H24ClN9O
    5. Molecular Weight: 429.90656
    6. EINECS: N/A
    7. Product Categories: Pharmaceuticals, Intermediates & Fine Chemicals;Inhibitors
    8. Mol File: 1370261-97-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: ≥21.5 mg/mL in DMSO; insoluble in EtOH; ≥83.2 mg/mL in H2O with gentle warming
    9. CAS DataBase Reference: PRT062607 (Hydrochloride)(CAS DataBase Reference)
    10. NIST Chemistry Reference: PRT062607 (Hydrochloride)(1370261-97-4)
    11. EPA Substance Registry System: PRT062607 (Hydrochloride)(1370261-97-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1370261-97-4(Hazardous Substances Data)

1370261-97-4 Usage

Uses

Used in Pharmaceutical Industry:
PRT062607 (Hydrochloride) is used as a therapeutic agent for the treatment of leukemia. Its application is based on its ability to inhibit the spleen tyrosine kinase (SYK), which is involved in the development and progression of leukemia. By targeting SYK, PRT062607 (Hydrochloride) can potentially suppress the growth of leukemia cells and improve the treatment outcomes for patients suffering from this disease.

Check Digit Verification of cas no

The CAS Registry Mumber 1370261-97-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,7,0,2,6 and 1 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1370261-97:
(9*1)+(8*3)+(7*7)+(6*0)+(5*2)+(4*6)+(3*1)+(2*9)+(1*7)=144
144 % 10 = 4
So 1370261-97-4 is a valid CAS Registry Number.

1370261-97-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-{[(1R,2R)-2-Aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl )phenyl]amino}-5-pyrimidinecarboxamide hydrochloride (1:1)

1.2 Other means of identification

Product number -
Other names 2-[[(1R,2S)-2-Aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide Hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1370261-97-4 SDS

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