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m-PEG10-amine, also known as methoxy-polyethylene glycol amine with an average molecular weight of 10 kDa, is a hydrophilic polymer that is commonly used in various applications due to its unique properties. It is reactive with activated NHS esters to form stable amide bonds, and the presence of the polyethylene glycol (PEG) spacer significantly increases its solubility in aqueous media. This characteristic makes m-PEG10-amine a versatile molecule for a wide range of applications, particularly in the fields of pharmaceuticals, biochemistry, and materials science.

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  • 1383658-09-0 Structure
  • Basic information

    1. Product Name: m-PEG10-amine
    2. Synonyms: m-PEG10-amine
    3. CAS NO:1383658-09-0
    4. Molecular Formula: C21H45NO10
    5. Molecular Weight: 471.5827
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1383658-09-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 518.9±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.065±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 8.74±0.10(Predicted)
    10. CAS DataBase Reference: m-PEG10-amine(CAS DataBase Reference)
    11. NIST Chemistry Reference: m-PEG10-amine(1383658-09-0)
    12. EPA Substance Registry System: m-PEG10-amine(1383658-09-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1383658-09-0(Hazardous Substances Data)

1383658-09-0 Usage

Uses

Used in Pharmaceutical Industry:
m-PEG10-amine is used as a drug conjugation agent for improving the solubility and pharmacokinetic properties of therapeutic molecules. The hydrophilic PEG spacer enhances the solubility of hydrophobic drugs in aqueous environments, leading to better absorption and distribution within the body. This, in turn, can result in increased bioavailability and reduced side effects.
Used in Bioconjugation:
m-PEG10-amine is used as a bioconjugation agent for the attachment of biologically active molecules, such as peptides, proteins, and nucleic acids, to various surfaces or carriers. The stable amide bond formed with activated NHS esters ensures the covalent attachment of these molecules, allowing for the creation of targeted drug delivery systems, biosensors, and other bioanalytical tools.
Used in Drug Delivery Systems:
m-PEG10-amine is used as a component in the design and synthesis of drug delivery systems, such as nanoparticles, liposomes, and hydrogels. The hydrophilic PEG spacer can improve the stability and circulation time of these systems in the body, while also providing a platform for the attachment of therapeutic molecules. This can lead to enhanced targeting and controlled release of drugs, ultimately improving the efficacy and safety of treatments.
Used in Diagnostics:
m-PEG10-amine is used as a component in the development of diagnostic tools, such as imaging agents and biosensors. The hydrophilic PEG spacer can improve the solubility and biocompatibility of these diagnostic agents, allowing for better targeting and detection of specific biological markers or disease indicators.
Used in Materials Science:
m-PEG10-amine is used as a building block for the synthesis of various materials with tailored properties, such as hydrogels, block copolymers, and self-assembling structures. The hydrophilic PEG spacer can provide unique properties, such as enhanced water absorption, improved biocompatibility, and tunable mechanical properties, making these materials suitable for a wide range of applications, including tissue engineering, wound healing, and environmental remediation.

Check Digit Verification of cas no

The CAS Registry Mumber 1383658-09-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,8,3,6,5 and 8 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1383658-09:
(9*1)+(8*3)+(7*8)+(6*3)+(5*6)+(4*5)+(3*8)+(2*0)+(1*9)=190
190 % 10 = 0
So 1383658-09-0 is a valid CAS Registry Number.

1383658-09-0Upstream product

1383658-09-0Downstream Products

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