Bromo-PEG6-t-butyl ester is a PEG (polyethylene glycol) linker that features a bromide group and a t-butyl protected carboxyl group. This molecule is designed to enhance solubility in aqueous media due to the hydrophilic PEG spacer. The bromide (Br) acts as an excellent leaving group for nucleophilic substitution reactions, while the t-butyl protected carboxyl group can be deprotected under acidic conditions, making it a versatile compound for various applications.
1393330-41-0
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Basic information
- Product Name: Bromo-PEG6-t-butyl ester
- Synonyms: Bromo-PEG6-t-butyl ester;Bromo-PEG7-t-butyl ester;Br-PEG6-t-butyl ester;Br-PEG6-CH2CH2COOtBu
- CAS NO:1393330-41-0
- Molecular Formula: C19H37BrO8
- Molecular Weight: 473.39628
- EINECS: N/A
- Product Categories: N/A
- Mol File: 1393330-41-0.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 489.9±40.0 °C(Predicted)
- Flash Point: N/A
- Appearance: /
- Density: 1.192±0.06 g/cm3(Predicted)
- Refractive Index: N/A
- Storage Temp.: N/A
- Solubility: N/A
- CAS DataBase Reference: Bromo-PEG6-t-butyl ester(CAS DataBase Reference)
- NIST Chemistry Reference: Bromo-PEG6-t-butyl ester(1393330-41-0)
- EPA Substance Registry System: Bromo-PEG6-t-butyl ester(1393330-41-0)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany:
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 1393330-41-0(Hazardous Substances Data)
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1393330-41-0 Usage
Uses
Used in Bioconjugation and Drug Synthesis:Bromo-PEG6-t-butyl ester is used as a bioconjugation agent for the attachment of biomolecules to other molecules or surfaces. The bromide group facilitates nucleophilic substitution reactions, allowing for the efficient coupling of biomolecules such as proteins, peptides, or small molecules to the PEG linker. This enhances the stability, solubility, and bioavailability of the biomolecule, making it suitable for various therapeutic and diagnostic applications.
Used in Drug Delivery Systems:
In the pharmaceutical industry, Bromo-PEG6-t-butyl ester is used as a component in the development of drug delivery systems. The PEG linker can be used to modify drug molecules, improving their solubility, circulation time, and bioavailability. Additionally, the t-butyl protected carboxyl group can be deprotected under acidic conditions, allowing for controlled release of the drug in specific environments, such as tumor tissues or intracellular compartments.
Used in Polymer Science:
Bromo-PEG6-t-butyl ester is used as a building block in the synthesis of various polymers and copolymers. The PEG linker can be incorporated into polymer structures to enhance their hydrophilicity, biocompatibility, and solubility. This makes it an attractive option for the development of novel materials for applications in coatings, adhesives, and other industrial products.
Used in Chemical Synthesis:
Bromo-PEG6-t-butyl ester is used as an intermediate in the synthesis of various chemical compounds. The bromide group can be replaced by a wide range of nucleophiles, allowing for the creation of diverse PEGylated products with tailored properties. This makes it a valuable tool for the development of new molecules with potential applications in various fields, including pharmaceuticals, materials science, and environmental chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 1393330-41-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,9,3,3,3 and 0 respectively; the second part has 2 digits, 4 and 1 respectively.Calculate Digit Verification of CAS Registry Number 1393330-41:
(9*1)+(8*3)+(7*9)+(6*3)+(5*3)+(4*3)+(3*0)+(2*4)+(1*1)=150
150 % 10 = 0
So 1393330-41-0 is a valid CAS Registry Number.
1393330-41-0Upstream product
1393330-41-0Downstream Products
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Bromo-PEG6-t-butyl ester
