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4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride is a bicyclic amine derivative with the molecular formula C8H16ClNO, commonly utilized in medicinal chemistry as a building block for the synthesis of various pharmaceuticals. It is an important intermediate in the creation of drugs, particularly antipsychotic and antidepressant medications, and is valued for its role as a chiral auxiliary in the asymmetric synthesis of compounds. The hydrochloride salt form enhances its stability and water solubility, facilitating easier handling and administration in pharmaceutical formulations.

1403864-74-3

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1403864-74-3 Usage

Uses

Used in Pharmaceutical Industry:
4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride is used as a key intermediate for the synthesis of various drugs, particularly for the development of antipsychotic and antidepressant medications. Its role in the synthesis process is crucial due to its ability to contribute to the formation of the desired active pharmaceutical ingredients.
Used as a Chiral Auxiliary:
In the field of asymmetric synthesis, 4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride is used as a chiral auxiliary to assist in the production of enantiomerically pure compounds. This application is vital for ensuring the desired stereochemistry in the final pharmaceutical product, which can significantly impact the drug's efficacy and safety.
Used in Drug Formulation:
The hydrochloride salt form of 4-Aminobicyclo[2.2.2]octan-1-ol is used to improve the stability and water solubility of pharmaceutical formulations. This enhancement makes the compound easier to handle and administer, which is essential for the development of effective drug delivery systems.

Check Digit Verification of cas no

The CAS Registry Mumber 1403864-74-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,0,3,8,6 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1403864-74:
(9*1)+(8*4)+(7*0)+(6*3)+(5*8)+(4*6)+(3*4)+(2*7)+(1*4)=153
153 % 10 = 3
So 1403864-74-3 is a valid CAS Registry Number.

1403864-74-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Aminobicyclo[2.2.2]octan-1-ol hydrochloride

1.2 Other means of identification

Product number -
Other names 1-aminobicyclo[2.2.2]octan-4-ol,hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1403864-74-3 SDS

1403864-74-3Downstream Products

1403864-74-3Relevant articles and documents

SUBSTITUTED DIAMINOCARBOXAMIDE AND DIAMINOCARBONITRILE PYRIMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

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Page/Page column 137, (2012/11/07)

Provided herein are Diaminopyrimidine Compounds having the following structures: wherein R1, R2, R3, and R4 are as defined herein, compositions comprising an effective amount of a Diaminopyrimidine Compound, and methods for treating or preventing liver fibrotic disorders or a condition treatable or preventable by inhibition of a JNK pathway.

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