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Benzyl-PEG3-CH2CO2tBu is a PEG (polyethylene glycol) linker with a benzyl and t-butyl protecting group. Both protecting groups are acid labile, which means they can be removed under acidic conditions. The hydrophilic PEG linker enhances the water solubility of the compound in aqueous media, making it a versatile molecule for various applications.

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  • 1643957-26-9 Structure
  • Basic information

    1. Product Name: Benzyl-PEG3-CH2CO2tBu
    2. Synonyms: Benzyl-PEG3-CH2CO2tBu;1643957-26-9;Benzyl-PEG2-CH2-Boc;tert-butyl 2-(2-(2-(benzyloxy)ethoxy)ethoxy)acetate;TERT-BUTYL 2-{2-[2-(BENZYLOXY)ETHOXY]ETHOXY}ACETATE;SCHEMBL16346595;DTXSID101141882;AKOS040741312;BP-22243;WS-00504;HY-130172;CS-0105394;C70800;tert-butyl 2-[2-(2-phenylmethoxyethoxy)ethoxy]acetate;Acetic acid, 2-[2-[2-(phenylmethoxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
    3. CAS NO:1643957-26-9
    4. Molecular Formula: C17H26O5
    5. Molecular Weight: 310.4
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1643957-26-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Benzyl-PEG3-CH2CO2tBu(CAS DataBase Reference)
    10. NIST Chemistry Reference: Benzyl-PEG3-CH2CO2tBu(1643957-26-9)
    11. EPA Substance Registry System: Benzyl-PEG3-CH2CO2tBu(1643957-26-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1643957-26-9(Hazardous Substances Data)

1643957-26-9 Usage

Uses

Used in Pharmaceutical Industry:
Benzyl-PEG3-CH2CO2tBu is used as a protecting group for drug molecules to improve their stability and solubility in aqueous environments. The acid-labile nature of the protecting groups allows for controlled release of the active pharmaceutical ingredient under specific conditions, such as the acidic environment within certain cells or tissues.
Used in Drug Delivery Systems:
Benzyl-PEG3-CH2CO2tBu is used as a component in the design of drug delivery systems, particularly for targeted drug delivery. The PEG linker can be attached to drug molecules or nanoparticles, enhancing their solubility and biocompatibility. The acid-labile protecting groups ensure that the drug is released at the desired site, such as tumor cells, where the acidic environment can trigger the removal of the protecting groups and release the active drug.
Used in Chemical Synthesis:
Benzyl-PEG3-CH2CO2tBu can be used as an intermediate in the synthesis of more complex molecules, such as bioconjugates or drug-delivery vehicles. The acid-labile protecting groups allow for selective deprotection and functionalization of the molecule at different stages of the synthesis process.
Used in Materials Science:
The hydrophilic nature of the PEG linker in Benzyl-PEG3-CH2CO2tBu can be exploited in the development of hydrogels, coatings, or other materials with specific properties. The acid-labile protecting groups can be used to control the degradation or release of other molecules from these materials under specific conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 1643957-26-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,4,3,9,5 and 7 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1643957-26:
(9*1)+(8*6)+(7*4)+(6*3)+(5*9)+(4*5)+(3*7)+(2*2)+(1*6)=199
199 % 10 = 9
So 1643957-26-9 is a valid CAS Registry Number.

1643957-26-9Upstream product

1643957-26-9Downstream Products

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