1658490-50-6 Usage
Uses
Used in Medicinal Chemistry:
2,6-bis((R)-4-isobutyl-4,5-dihydrooxazol-2-yl)pyridine is used as a structural motif in the development of new pharmaceuticals for its potential to contribute to the biological activity of compounds. The presence of oxazoles and pyridines, which are common in many bioactive molecules, makes 2,6-bis((R)-4-isobutyl-4,5-dihydrooxazol-2-yl)pyridine a promising candidate for further research and development in the field of drug discovery.
Used in Drug Design and Synthesis:
In the pharmaceutical industry, 2,6-bis((R)-4-isobutyl-4,5-dihydrooxazol-2-yl)pyridine is utilized as a building block or a core structure in the design and synthesis of novel drug molecules. Its unique stereochemistry and the ability to form stable complexes with other molecules make it valuable for creating drugs with enhanced efficacy and selectivity.
Check Digit Verification of cas no
The CAS Registry Mumber 1658490-50-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,5,8,4,9 and 0 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1658490-50:
(9*1)+(8*6)+(7*5)+(6*8)+(5*4)+(4*9)+(3*0)+(2*5)+(1*0)=206
206 % 10 = 6
So 1658490-50-6 is a valid CAS Registry Number.
1658490-50-6Relevant articles and documents
Visible light photocatalytic asymmetric synthesis of pyrrolo[1,2-: A] indoles via intermolecular [3+2] cycloaddition
Casado-Sánchez, Antonio,Domingo-Legarda, Pablo,Cabrera, Silvia,Alemán, José
supporting information, p. 11303 - 11306 (2019/09/30)
The intermolecular diastereoselective and enantioselective synthesis of pyrrolo[1,2-a]indoles is developed through a [3+2] cycloaddition between silyl-indole derivatives and α,β-unsaturated N-acyl oxazolidinones by merging photocatalysis and Lewis acid catalysis.
Enantioselective conjugate additions of α-amino radicals via cooperative photoredox and Lewis acid catalysis
Ruiz Espelt, Laura,McPherson, Iain S.,Wiensch, Eric M.,Yoon, Tehshik P.
supporting information, p. 2452 - 2455 (2015/03/04)
We report the highly enantioselective addition of photogenerated α-amino radicals to Michael acceptors. This method features a dual-catalyst protocol that combines transition metal photoredox catalysis with chiral Lewis acid catalysis. The combination of these two powerful modes of catalysis provides an effective, general strategy to generate and control the reactivity of photogenerated reactive intermediates.
