1776114-17-0 Usage
Pyrrolidine derivative
A modified pyrrolidine ring structure
1-benzyl-4,4-difluoropyrrolidin-3-ol is derived from a pyrrolidine ring, which is a five-membered ring containing one nitrogen atom and four carbon atoms.
Benzyl group
A phenyl group attached to a methyl group
The benzyl group is a part of the 1-benzyl-4,4-difluoropyrrolidin-3-ol structure, consisting of a phenyl ring (a six-membered ring with alternating single and double bonds) connected to a methyl group (a single carbon atom with three hydrogen atoms).
Two fluorine atoms
Attached to the pyrrolidine ring
The presence of two fluorine atoms in the compound suggests that they are attached to the pyrrolidine ring, potentially influencing the compound's reactivity, stability, and pharmacokinetic properties.
Potential pharmaceutical applications
Development of new drugs
Due to its unique structure, 1-benzyl-4,4-difluoropyrrolidin-3-ol may have biological activity and could be used in the synthesis of pharmaceuticals, making it a valuable compound for drug development.
Biological activity
Possible interaction with biological systems
The presence of the benzyl group and difluoropyrrolidin-3-ol moiety in the structure of 1-benzyl-4,4-difluoropyrrolidin-3-ol suggests that it may have biological activity, which could be relevant for its use in the pharmaceutical industry.
Pharmacokinetic properties
Influence on absorption, distribution, metabolism, and excretion
The difluoropyrrolidin-3-ol moiety in the compound may contribute to its pharmacokinetic properties, affecting how the compound is absorbed, distributed, metabolized, and excreted by the body.
Medicinal chemistry research
A valuable building block
1-benzyl-4,4-difluoropyrrolidin-3-ol may be a useful building block in medicinal chemistry research, as its unique structure and properties can be utilized in the synthesis of new pharmaceutical compounds.
Further studies and research needed
To fully understand potential uses and properties
Additional research is required to explore the potential applications and properties of 1-benzyl-4,4-difluoropyrrolidin-3-ol in the pharmaceutical industry, including its biological activity, pharmacokinetic properties, and potential drug interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 1776114-17-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,7,7,6,1,1 and 4 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1776114-17:
(9*1)+(8*7)+(7*7)+(6*6)+(5*1)+(4*1)+(3*4)+(2*1)+(1*7)=180
180 % 10 = 0
So 1776114-17-0 is a valid CAS Registry Number.
1776114-17-0Relevant articles and documents
6-HETEROARYLOXY BENZIMIDAZOLES AND AZABENZIMIDAZOLES AS JAK2 INHIBITORS
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Paragraph 0925, (2021/11/13)
The present disclosure provides 6-heteroaryloxy benzimidazole and azabenzimidazole compounds and compositions thereof useful for inhibiting JAK2.
DIHYDROPYRIMIDINE COMPOUND AND PREPARATION METHOD AND USE THEREOF
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Paragraph 0139; 0142, (2019/07/18)
The present invention relates to a dihydropyrimidine compound having an antiviral activity, a pharmaceutical composition comprising same, a preparation method therefor and the uses thereof in the prevention or treatment of viral diseases including, but no
COMPOUNDS USEFUL AS KINASE INHIBITORS
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Paragraph 00405, (2017/07/14)
This invention relates to novel compounds. The compounds of the invention are tyrosine kinase inhibitors. Specifically, the compounds of the invention are useful as inhibitors of Bruton's tyrosine kinase (BTK).The invention also contemplates the use of the compounds for treating conditions treatable by the inhibition of Bruton's tyrosine kinase, for example cancer, lymphoma, leukemia and immunological diseases.
Synthesis of Small 3-Fluoro- and 3,3-Difluoropyrrolidines Using Azomethine Ylide Chemistry
McAlpine, Indrawan,Tran-Dubé, Michelle,Wang, Fen,Scales, Stephanie,Matthews, Jean,Collins, Michael R.,Nair, Sajiv K.,Nguyen, Mary,Bian, Jianwei,Alsina, Luis Martinez,Sun, Jianmin,Zhong, Jiaying,Warmus, Joseph S.,O'Neill, Brian T.
, p. 7266 - 7274 (2015/07/28)
Here, we report accessing small 3-fluoropyrrolidines and 3,3-difluoropyrrolidines through a 1,3-dipolar cycloaddition with a simple azomethine ylide and a variety of vinyl fluorides and vinyl difluorides. We demonstrate that vinyl fluorides within α,β-unsaturated, styrenyl and even enol ether systems can participate in the cycloaddition reaction. The vinyl fluorides are relatively easy to synthesize through a variety of methods, making the 3-fluoropyrrolidines very accessible.
PURINE DERIVATIVES
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Paragraph 0734; 0735, (2015/05/26)
The present invention relates to compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Q, G, ring A, ring B, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, R18, R19, R20, R21, R22, R23, R24, and m are defined herein. The novel purine derivatives are useful in the treatment of abnormal cell growth, such as cancer, in mammals. Additional embodiments relate to pharmaceutical compositions containing the compounds and to methods of using the compounds and compositions in the treatment of abnormal cell growth in mammals.
